Controlled Release Drug Delivery Market Size, Share & Trends Analysis Report By Technology (Targeted Delivery, Transdermal), By Release Mechanism, By Application- Global Industry Analysis, Share, Growth, Regional Outlook and Forecasts, 2022-2030

According to Nova one advisor, the global Controlled Release Drug Delivery market size is expected to hit around USD 111.14 billion by 2030 from valued at USD 47.39 billion in 2021 and growing at a CAGR of 11.5% from 2022 to 2030.

The benefits associated with controlled release drug delivery systems such as increased therapeutic efficacy, fewer side effects, and low treatment cost are the factors driving the growth of the market during the forecast period. These technologies offer various benefits over traditional delivery forms. Reduced dosage and dosage frequency, enhanced patient compliance, less gastrointestinal side effects, uniform drug effect, improved drug efficacy and safety, and reduced fluctuation of plasma drug levels are some of the major advantages offered by controlled release technology.

The presence of multiple in-vivo biological barriers that affect the absorption, bioavailability, and stability of the drug has opened a wide horizon for controlled release drug delivery products. For instance, a controlled release drug delivery system has enabled the delivery of even large and complex molecules such as DNA/RNA, proteins, and polypeptides. Additionally, the rising awareness among healthcare professionals, regarding the advantage of controlled release drug delivery systems over conventional systems is expected to drive the demand for the market in long run.

The rapidly increasing geriatric and pediatric population is one of the major factors impacting the growth of the market. Since a major proportion of prescription non-adherence cases is observed in this age group of the population. Innovations in various drug delivery systems have been providing the geriatric and pediatric populations with easy solutions, which are further propelling the market. Controlled release of drugs allows a reduction in overdose in the elderly population as they can be altered according to the required dosage over a specific period of time.

Report Scope of the Controlled Release Drug Delivery Market

Report Coverage


Market Size

USD 111.14 Billion by 2030

Growth Rate

CAGR of 11.5% from 2022 to 2030

Largest Market

North America

Fastest Growing Market

Asia Pacific

Base Year


Forecast Period

2022 to 2030

Segments Covered

 Technology, release mechanism, application and Region,

Companies Mentioned

Orbis Biosciences, Inc.; Merck and Co., Inc.; Alkermes plc; Johnson and Johnson; Coating Place, Inc.; Corium International, Inc.; Depomed, Inc.; Pfizer, Inc; Aradigm Corporation; Capsugel


Key Takeaways:

  • By Application, the India Controlled Release Drug Delivery market was valued at USD 1.9 Billion in 2021 and expected to witness growth at a CAGR of 14.9% from 2022 to 2030.
  • Based on application, oral controlled release systems held the largest share in the market in 2021 owing to increasing usage and ease of convenience offered for the administration of medication
  • Targeted drug delivery is poised to be the fastest-growing technology segment during the forecast period owing to its various benefits such as increased therapeutic efficacy coupled with increased safety
  • The osmotic delivery segment, based on activation modulation drug delivery systems, is likely to witness the highest CAGR due to its ability to not be affected by various factors, such as pH, food consumption, and gastrointestinal motility

Technology Insights

Targeted delivery held the largest market share of more than 24.0% in 2021 as a large number of market participants have a strong portfolio for the technology. Targeted delivery offers the preferred site of action and can aid in allowing drugs to be away from sites that might lead to drug toxicity. Since these systems provide increased bioavailability, targeted technologies provide localization of drug, which leads to improved absorption, reduced fluctuation in circulating drug levels, and low risk of side effects it’s a commonly preferred drug delivery technology.

The rising demand to improve the shelf-life and achieve controlled drug release of highly complex and unstable molecules such as proteins, vitamins, and antioxidants is expected to foster the growth of the microencapsulation segment over the forecast period. For instance, vitamin A is characterized by poor water solubility and chemical stability, but when microencapsulated the shelf life of the product increases, concomitantly helping in achieving controlled drug release.

Implantable systems provide improved efficiency, reduced side effects, convenience, and ensure linear delivery of drugs over a specified period. Coacervates represent a novel class of drug delivery vehicles, developed as carriers of small molecule drugs and proteins. These include heparin-based coacervates holding synthetic polycations for controlled delivery of growth factors. With the increasing usage of these systems, they are anticipated to command a considerable share in the controlled release drug delivery market in near future.

Release Mechanism Insights

The feedback-regulated drug delivery systems accounted for a large share of 27.3% in 2021 owing to their therapeutic efficiency in the treatment of disorders such as diabetes. Additionally, the increasing R&D activities being conducted to capitalize on the potential of feedback-regulated controlled drug delivery systems as antidotes are expected to aid the market growth.

Chemically activated systems consist of pH activated, hydrolysis activated, and enzyme activated systems. The ability to respond promptly and specifically to the metabolite of interest that results in improved drug therapy is the factor driving the growth of the segment. For instance, optimum and controlled release of insulin is established in hyperglycemic patients using an enzyme-activated release mechanism.

In the recent past, chemically activated delivery systems have gained tremendous popularity. Market players are also investing in the segment in order to strengthen their portfolios. For instance, LYRICA Pregabalin and QuilliChew ER chewable tablets, marketed by Pfizer, Inc., are chemically activated delivery systems that offer controlled release. The segment is projected to represent a sizeable share in the market throughout the forecast horizon.

Application Insights

The oral controlled segment was the leading revenue contributor in 2021 with a share of more than 37.1% owing to its frequent usage and availability. Metered dose inhaler is another lucrative segment that is expected to grow at a significant rate over the forecast period. Rising prevalence of respiratory disorders, frequent product, and technological advancements are the factors expected to drive the growth of the segment in long run. For instance, Gofire Inc, a medical technology company introduced a metered dose inhaler in 2019,that features a unique dose completion alert signal assuring accurate dosing. Furthermore, Aradigm Corporation’s current product pipeline consists of three drugs for treatment of bronchiectasis, cystic fibrosis, and smoking cessation that make use of metered dose inhalers as they are a relatively easy way to administer drugs.

The injectable segment is projected to grow at the fastest pace during the forecast period owing to wide product diversity and usage in the treatment of various diseases. Long-acting injectables are preferred to conventional forms of delivery as they offer several advantages, including predictable drug release profile during a definite period of time, enhanced patient compliance, improved systemic availability of drugs, ease of application, and thus an overall reduction in medical costs incurred.

Regional Insights

In 2021, North America was the leading regional market in the global arena with over 43.8% market share. Supportive government initiatives taken for the development of controlled release drug delivery and growing investments in R&D are expected to propel the market growth in the region. Besides this, the presence of prominent market players in promoting the adoption of controlled release drug delivery systems. The increasing burden of chronic diseases such as cancer, diabetes, and cardiac disorders is aiding the market growth. Spiraling utilization of controlled release drug delivery systems for the treatment of hypertension is one of the key trends escalating the growth of the regional market.

Europe accounted for the second-largest share in 2019 owing to increasing research and developmental activities and the presence of major pharmaceutical companies in the region. With the significant rise in patients suffering from chronic diseases such as cancer, diabetes, and COPD, the regional market is poised to tread along a healthy growth track over the coming years. Asia Pacific is likely to witness the highest CAGR during the forecast period. The region has been gaining global attention due to increasing development in the pharmaceutical industry. Rapid expansion in the Indian and Chinese pharmaceutical industries is positively affecting the market in the region. The presence of a large geriatric population in Japan is another major factor triggering product adoption.

Some of the prominent players in the Controlled Release Drug Delivery Market include:

  • Orbis Biosciences, Inc.
  • Merck and Co., Inc.
  • Alkermes plc
  • Johnson and Johnson
  • Coating Place, Inc.
  • Corium International, Inc.
  • Depomed, Inc.
  • Pfizer, Inc.
  • Aradigm Corporation
  • Capsugel

Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2017 to 2030. For this study, Nova one advisor, Inc. has segmented the global Controlled Release Drug Delivery market

  • Technology
    • Wurster Technique
    • Coacervation
    • Micro Encapsulation
    • Implants
    • Transdermal
    • Targeted Delivery
    • Others (Microelectromechanical Technology, Liposomes)
  • Release Mechanism
    • Polymer Based Systems
    • Micro Reservoir Partition Controlled Drug Delivery Systems
    • Feedback Regulated Drug Delivery Systems
    • Activation-modulated Drug Delivery Systems
      • Osmotic Pressure Activated
      • Hydrodynamic Pressure Activated
      • Vapor Pressure Activated
      • Mechanically Activated
      • Magnetically Activated
    • Chemically Activated
      • pH Activated
      • Hydrolysis Activated
      • Enzyme Activated
  • Application
    • Metered Dose Inhalers
    • Injectable
    • Transdermal and Ocular Patches
    • Infusion Pumps
    • Oral Controlled-drug delivery Systems
    • Drug Eluting Stents

By Geography

North America

  • U.S.
  • Canada


  • Germany
  • France
  • United Kingdom
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Southeast Asia
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Rest of Latin America

Middle East & Africa (MEA)

  • GCC
  • North Africa
  • South Africa
  • Rest of Middle East & Africa

Key Benefits for Stakeholders

  • This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the global Controlled Release Drug Delivery industry analysis from 2022 to 2030 to identify the prevailing Controlled Release Drug Delivery industry opportunity.
  • The market research is offered along with information related to key drivers, restraints, and opportunities.
  • Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
  • In-depth analysis of the global Controlled Release Drug Delivery industry segmentation assists to determine the prevailing market opportunities.
  • Major countries in each region are mapped according to their revenue contribution to the global market.
  • Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
  • The report includes the analysis of the regional as well as global Controlled Release Drug Delivery industry trends, key players, market segments, application areas, and market growth strategies.



Report Detail

  • Report Code:7141
  • No. of Pages:150+
  • Format:PDF/PPT/Excel

Proceed To Buy

USD 3500
USD 7000

Customization Offered

  • check-imgCross-segment Market Size and Analysis for Mentioned Segments
  • check-imgAdditional Company Profiles (Upto 5 With No Cost)
  • check-img Additional Countries (Apart From Mentioned Countries)
  • check-img Country/Region-specific Report
  • check-img Go To Market Strategy
  • check-imgRegion Specific Market Dynamics
  • check-imgRegion Level Market Share
  • check-img Import Export Analysis
  • check-imgProduction Analysis
  • check-imgOthers