Bioactive fillings are surface reactive glass-ceramic biomaterials and have interaction with biological tissues. Bioactive fillings have biocompatibility and bioactivity and thus have a high application as implant material in the human body to repair and replace diseased tissue. Bioactive fillings reacts with the biological tissues in two phases. In the first phase, alkali metal ions are leached from the glass and replaced with hydrogen ions and in the second phase, the Si-O-Si bonds in the silica matrix undergo hydrolysis, yielding a gel-like surface layer rich on Si-O-H groups. In the ultimate stage, calcium phosphate-rich layer forms over the surface of the filling, sealing any further leaching. Bioactive fillings, interact with the body, and have been used in orthopaedics for decades. Bioactive fillings are made from compounds such as silicon oxide, calcium oxide, and phosphorous oxide, and has antimicrobial effect due to the release of calcium and phosphate ions which have an antibacterial activity and also tend to neutralize the local acidic pH. Bioactive fillings prolong the life of fillings because their antibacterial effects and replacement of lost minerals.
Segments
The global bioactive fillings market has been segmented on the basis of material, applications and end user.
Based on the material, the market has been segmented as silicon dioxide based, calcium oxide based, phosphorus pentoxide based, and sodium oxide based.
Based on the applications, the market has been segmented as orthopedic, dental, tissue engineering and others.
Based on the end user, the market has been segmented as orthopedic hospitals, dental hospitals, research and academics and others.
Key Players in the Global Bioactive fillings Market
Some of the key players profiled in the report are Septodont, Inc., DePuy Synthes, Medtronic, Stryker, Zimmer Biomet, SCHOTT AG, Aap Implantate AG, GNI GROUP LTD., Arthrex, Inc., Baxter, and others
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