Global Total Ankle Replacement Market Size, Share, Forecast Report, 2020-2027

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The global total ankle replacement market is estimated to grow at a CAGR of nearly 7.0% during the forecast period. Rising prevalence of osteoarthritis, rising demand for minimally invasive joint replacement procedures, and increasing geriatric population are the major factors driving the demand for total ankle replacement procedures. Increasing prevalence of osteoarthritis was reported both in the adults and ageing population. As per the Centers for Disease Control and Prevention (CDC), during the period 2013-2015, nearly 54.4 million US adults (22.7%) annually had some form of rheumatoid arthritis, arthritis, gout, fibromyalgia, or lupus.



The adults suffering from arthritis differs by state, which ranges from 17.2% in Hawaii to 33.6% in West Virginia in 2015. Based on the county, the percentage of adults with arthritis differs considerably, ranging from 11.2% to 42.7% in 2015. By 2040, it was estimated by the CDC that 78 million (26%) US adults aged 18 years and older will be diagnosed with arthritis. The number of osteoarthritis cases will also increase due to the rising geriatric population as it is one of the major causes of disability in people aged more than 65 years.



This rising prevalence will accelerate the demand for total ankle replacement procedure for patients with osteoarthritis and rheumatoid arthritis. The procedure can provide relief from pain and maintain motion in the arthritic ankle joint. Total ankle replacement is an alternative to ankle fusion procedure which can relieve pain, however, eliminates motion in the joint. In July 2018, Wright Medical Group N.V. declared that the total ankle replacement procedures using their devices surpassed 30,000 since 2008. The company offers a complete range of primary to revision total ankle system which include INBONE Total Ankle System, INFINITY Total Ankle System, PROPHECY Preoperative Navigation, and INVISION Total Ankle Revision System.



INBONE Total Ankle System is one of the most commonly used total ankle replacement device owing to its increased tibiotalar stability, talar fixation, and comprehensive sizing. Other commonly used total ankle replacement systems include INIFINITY (Wright), STAR (Stryker), Trabecular Metal Total Ankle (Zimmer Biomet), and Salto Talaris (Integra Lifesciences). As a result, these players have a major dominance in the market and other market players are also launching more safe and effective total ankle replacement systems to make a significant position in the market. In November 2019, Stryker declared an agreement to acquire Wright Medical Group to further strengthen its trauma and extremities business.



Market Segmentation



The global total ankle replacement market is segmented based on the design, material, and application. Based on design, the market is classified into BOX, scandinavian, mobility, zenith, salto, hintegra, and others. Based on material, the market is segmented into metal and plastic. Based on application, the market is segmented into osteoarthritis and rheumatoid arthritis.



Metal finds its significant application in the total ankle replacement systems



Metals are being most commonly used in medical implants as it contains unique and normally useful surface and biological properties, such as heat transduction and biocompatible strain. As compared to polymers which are usually intended to degrade by erosion or hydrolysis, metals degrade in the body by either galvanic corrosion or oxidative corrosion. Moreover, owing to the fracture toughness and high mechanical strength, they are useful for load-bearing applications. The most common metals and alloys that are utilized in implants such as titanium, stainless steel, and nickel-titanium alloy (nitinol), and cobalt-chrome alloy. Trabecular Metal Total Ankle by Zimmer Biomet and INBONE Total Ankle System by Wright are the major instances of a metal-based total ankle replacement system that are designed to reproduce the natural flexibility and preserve motion in ankle arthroplasty patients.



Regional Outlook



The market is segmented into four major regions including North America, Europe, Asia-Pacific, and Rest of the World (RoW). In 2019, North America is expected to hold a significant share in the market owing to the rising number of joint replacement procedures owing to the increasing prevalence of arthritis in the region. Asia-Pacific is estimated to witness potential growth during the forecast period owing to the rising adoption of minimally invasive procedures for joint replacement procedures and rising geriatric population base. Rising sports injuries are further anticipated to drive the demand for total ankle replacement procedures in the region.



Market Players Outlook



The major players operating in the market include Johnson & Johnson Services, Inc., Stryker Corp., Integra LifeSciences Corp., Zimmer Biomet Holdings, Inc., and Exactech, Inc. The market players are focusing on strategies including mergers and acquisitions, product launches, and partnerships and collaborations, which intends to generate significant revenue by offering more safe, reliable, cost-effective, and efficient total ankle replacement system. For instance, in February 2020, In2Bones SAS launched Quantum total ankle replacement for the treatment of patients suffering from arthritis and is designed to increase stability, improve patient mobility, and technologically advance implant placement based on patient-specific anatomy. In comparison to the currently available total ankles on the market, this new system has anatomically designed talus with a dual radius of curvature that improves dorsi and the plantar flexion of the patient.