The global heart-lung machine market size was exhibited at USD 2.21 billion in 2023 and is projected to hit around USD 4.43 billion by 2033, growing at a CAGR of 7.2% during the forecast period of 2024 to 2033.
Key Takeaways:
- North America accounted for the largest revenue share of 43.0% in 2023.
- Based on component, the oxygenators segment accounted for the largest revenue share of 25.87% in 2023.
- Based on application type, the coronary artery bypass grafting (CABG) segment accounted for the largest revenue share of 31.07% in 2023.
- On the basis of end-use, the hospital's segment accounted for the largest revenue share of 82.0% in 2023.
Market Overview
The Heart-Lung Machine market, also referred to as the cardiopulmonary bypass (CPB) machine market, forms a critical backbone of modern cardiac surgery. These machines temporarily take over the functions of the heart and lungs during complex surgical procedures such as coronary artery bypass grafting (CABG), heart valve repair or replacement, heart and lung transplants, and pediatric congenital heart surgeries. They enable surgeons to operate on a still and bloodless heart, ensuring precise and safe surgical outcomes.
A heart-lung machine typically consists of multiple components—including pumps, oxygenators, heat exchangers, cannulae, blood reservoirs, and integrated monitoring systems—working in tandem to oxygenate and circulate blood while regulating body temperature. With growing global prevalence of cardiovascular diseases (CVDs), an aging population, rising incidence of lifestyle-related conditions like hypertension and diabetes, and expanding access to advanced surgical care in emerging economies, the market is poised for steady expansion.
Technological innovation, particularly in compact design, automation, real-time monitoring, and biocompatible materials, is redefining CPB systems, making them safer and more user-friendly. Moreover, the increasing adoption of minimally invasive cardiac surgeries and integration with extracorporeal membrane oxygenation (ECMO) systems are unlocking new dimensions for market growth.
Major Trends in the Market
-
Miniaturization and Portability of CPB Machines: Demand for compact, mobile units to support off-site and emergency cardiac care.
-
Integration with ECMO and VAD (Ventricular Assist Devices): Dual-function systems supporting long-term extracorporeal circulation in critical care.
-
Artificial Intelligence and Automation: Use of AI in pump control, oxygenation regulation, and perfusion monitoring to enhance patient safety.
-
Growing Preference for Modular Systems: Customizable setups based on procedure complexity and patient demographics.
-
Increased Focus on Pediatric Cardiopulmonary Solutions: Tailored devices and cannulae for congenital cardiac procedures in neonates and infants.
-
Use of Biocompatible and Anticoagulant-Coated Materials: Reducing hemolysis and clot formation during prolonged perfusion.
-
Expansion of Hybrid Operating Rooms: Driving demand for machines compatible with imaging and interventional systems.
Heart-lung Machine Market Report Scope
Market Driver: Rising Global Burden of Cardiovascular Surgeries
A key driver for the heart-lung machine market is the increasing global demand for cardiac surgical interventions, particularly in coronary artery disease and valvular heart disease. According to the World Health Organization, cardiovascular diseases remain the leading cause of mortality worldwide, accounting for approximately 17.9 million deaths annually. The aging population, especially in developed regions, has led to a surge in elective cardiac procedures.
CABG, one of the most common cardiac surgeries, often requires cardiopulmonary bypass. In the U.S. alone, over 200,000 CABG procedures are performed annually. This, combined with rising awareness and access to surgical care in emerging economies such as India, Brazil, and China, is significantly driving market adoption. The expansion of tertiary and quaternary care hospitals, equipped with dedicated cardiac surgery departments, is further fueling demand for reliable and technologically advanced heart-lung machines.
Market Restraint: High Cost and Complexity of Operation
Despite their critical utility, heart-lung machines are capital-intensive medical devices, with prices ranging from several hundred thousand to over a million dollars depending on configuration. Their acquisition and maintenance represent a significant burden for mid-tier and rural hospitals, especially in low- and middle-income countries (LMICs). These machines also require highly trained perfusionists, limiting adoption in regions with workforce shortages.
Moreover, the complexity of operation, risk of complications such as systemic inflammatory response syndrome (SIRS), coagulation disturbances, and hemolysis during CPB, create barriers to broader acceptance. Regulatory approvals for new systems and components are stringent, further slowing market expansion in price-sensitive regions.
Market Opportunity: Integration of Advanced Monitoring and Automation Systems
A major opportunity lies in the development of integrated and intelligent heart-lung machines, equipped with real-time monitoring systems, automation protocols, and AI-based predictive analytics. Integration of blood gas analyzers, temperature monitors, and flow sensors directly into the machine allows dynamic adjustments during surgery, improving patient outcomes and reducing errors.
Manufacturers are also exploring closed-loop control systems that can automatically regulate perfusion flow based on patient-specific hemodynamic parameters. Combined with data logging and cloud connectivity, these smart systems enable better post-operative analysis and compliance with quality standards. CDMOs that develop software and hardware that make these machines more intuitive and interoperable with hospital information systems (HIS) are likely to gain a competitive edge.
Segmental Analysis
By Component
Pumps dominated the heart-lung machine market, as they form the core of any CPB system, responsible for maintaining adequate perfusion pressure and flow during surgery. Traditionally, roller pumps were widely used, but centrifugal pumps are now gaining traction due to reduced hemolysis risk and ease of priming. Advanced systems offer dual-pump setups to provide redundancy and enhanced safety. Pumps are increasingly being integrated with flow meters and bubble detectors to ensure accuracy and prevent embolism, enhancing their clinical utility.
Monitoring systems are the fastest-growing segment, reflecting the increasing demand for intraoperative visibility and precision. These systems enable continuous tracking of critical variables such as blood pressure, temperature, oxygen saturation, and flow rate. The integration of telemetry and touchscreen interfaces is driving this growth, as it allows perfusionists to make real-time adjustments. Portable and modular systems are being adopted in hybrid operating rooms, where cross-functional monitoring is essential.
By Application
Coronary artery bypass grafting (CABG) remains the dominant application segment, owing to its widespread use in managing ischemic heart disease. The majority of CABG procedures involve CPB, particularly in complex, multi-vessel, or high-risk cases. Heart-lung machines enable surgeons to temporarily halt cardiac activity, providing a stable and bloodless field for precise graft placement. The rising global burden of coronary heart disease, sedentary lifestyles, and increasing number of revascularization procedures continue to drive this segment.
Lung and heart transplants are the fastest-growing application segments, supported by advances in surgical techniques, donor matching, and organ preservation. In transplant procedures, heart-lung machines are essential for maintaining systemic circulation while replacing dysfunctional organs. ECMO-compatible systems are increasingly being used as bridge-to-transplant solutions in critical care. As transplantation programs expand across developing nations, demand for sophisticated CPB machines with dual functionality is expected to accelerate.
By End-use
Hospitals dominate the end-use category, as the majority of cardiothoracic procedures requiring CPB are performed in full-service tertiary care hospitals. These institutions are equipped with surgical theaters, ICU infrastructure, and experienced perfusion teams. Hospitals also account for repeat purchases and upgrades of heart-lung machines due to high surgical volumes and stringent equipment renewal policies. Public and private investments in healthcare infrastructure are increasing the number of cardiac centers within hospitals, boosting this segment.
Cardiac centers are the fastest-growing end-use segment, driven by the emergence of specialized standalone facilities focused exclusively on cardiovascular care. These centers often cater to elective and complex surgeries, including high-risk CABG, valve reconstructions, and pediatric cardiology. With growing emphasis on patient-centered, cost-effective care delivery, cardiac centers are investing in advanced heart-lung systems that offer better patient monitoring and reduced downtime between surgeries.
Regional Analysis
North America leads the global heart-lung machine market, with the U.S. accounting for the largest share. The region benefits from a high burden of cardiovascular diseases, a well-developed surgical infrastructure, and favorable reimbursement policies for cardiac procedures. The presence of leading manufacturers, such as LivaNova, Medtronic, and Terumo Cardiovascular, ensures early adoption of technological innovations. Furthermore, strong academic partnerships and clinical research funding enable rapid translation of R&D into commercial products.
Asia-Pacific is the fastest-growing region, propelled by rising healthcare investments, growing prevalence of cardiac disorders, and improvements in surgical capacity. Countries like China and India are rapidly expanding access to tertiary care and launching national cardiac health programs. Additionally, the availability of skilled cardiac surgeons and the introduction of mobile CPB units for rural outreach are supporting market growth. Government initiatives to promote indigenous manufacturing and public-private partnerships are making heart-lung machines more accessible in the region.
Some of the prominent players in the heart-lung machine market include:
- Medtronic
- Terumo Europe NV
- LivaNova, Inc.
- Getinge
- Braile Biomédica
- NIPRO
- Tianjin Welcome Medical Equipment Co., Ltd.
- ELITE LIFECARE
- Hemovent GmbH
- MERA (Senko Medical Instrument Mfg. Co., Ltd.)
- Technowood International Pte. Ltd.
Recent Developments
-
LivaNova (April 2025): Introduced a next-generation S5 heart-lung machine with advanced sensor arrays and wireless remote control for real-time perfusion adjustments.
-
Medtronic (March 2025): Announced integration of its CPB platform with electronic health record (EHR) systems to enhance surgical documentation and quality monitoring.
-
Terumo Cardiovascular (February 2025): Launched a compact, transportable CPB system designed for use in emergency cardiac surgeries and ECMO bridging.
-
Getinge Group (January 2025): Acquired a U.S.-based monitoring technology startup to strengthen its portfolio of smart perfusion systems and hybrid OR integration tools.
-
Braile Biomédica (December 2024): Expanded its production of CPB machines in Latin America, with a focus on localized manufacturing to reduce device costs.
Segments Covered in the Report
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Nova one advisor, Inc. has segmented the global heart-lung machine market.
Component
- Oxygenators
- Pumps
- Cannula
- Monitoring Systems
- Heat Exchanger Units
- Blood Reservoir
- Others
Application
- Coronary Artery Bypass Grafting (CABG)
- Heart Valve Surgeries
- Heart Transplant
- Lung Transplant
- Others
End-use
- Hospitals
- Cardiac Centers
- Others
By Region
- North America
- Europe
- Asia-Pacific
- Latin America
- Middle East & Africa (MEA)
Request Customization
Get a Sample
Get a Sample
Request Customization