Horseradish Peroxidase Market (Substrate: ABTS, OPD, TMB, and Others; Application: Immunoassays and Biosensors; Grade: Grade I, Grade II, and Grade III; and End User: Biopharmaceutical Companies, Academic & Research Centers, and Others) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2022 - 2030

The global Horseradish Peroxidase market gathered revenue around USD 65 Million in 2021 and market is set to grow USD 110 Million by the end of 2030 and is estimated to expand at a modest CAGR of 7.9% during the prediction period 2022 to 2030.

Growth Factors:

Horseradish peroxidase (HRP) is a well-known and commercially available enzyme. Its substrates are used in immunostaining and immunodetection of specific proteins and antigens. HRP is a widely used label, often conjugated to secondary antibodies in immunochemical applications such as immunohistochemistry, western blotting, and ELISA. North America dominated the global horseradish peroxidase market in 2020. The trend is anticipated to continue during the forecast period. Rise in research & development activities in the healthcare industry increases the demand for horseradish peroxidase. This is expected to drive the market in the region.

Report Scope of the Horseradish Peroxidase Market

Report Coverage


Market Size

US$ 110 Million by 2030

Growth Rate

CAGR of 7.9% from 2022 to 2030

Largest Market

North America

Fastest Growing Market

Asia Pacific

Base Year


Forecast Period

2022 to 2030

Segments Covered

Substrate, Grade, Application, End User and Region,

Companies Mentioned

 Abcam plc, Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, Merck KGaA, BBI Solutions, Takara Bio Company, Promega Corporation, Faizyme Laboratories, F. Hoffmann-La Roche Ltd., TOYOBO Co., Ltd., Oriental Yeast Co., Ltd., and GenScript..


ELISA Substrate Selection Determines End Results in Assay Systems

Manufacturers in the horseradish peroxidase market are gaining proficiency to develop enzymes with a range of sensitivities that play an instrumental role in different detection methods. They are increasing awareness about careful selection of ELISA substrates in order to obtain best results in assay systems. As such, ELISA substrates differ in price, ease-of-use, and sensitivity. Hence, researchers must opt for a variety of procedures to bring ELISA substrates in the working condition. The preparation of substrates plays a key role in detecting signals in assay systems. However, companies in the horseradish peroxidase market are increasing efforts to boost the availability of substrates that are in ready-to-use forms.

There is a growing awareness about various optimization methods for ELISA substrates, which help to deliver better results in assay systems. Manufacturers are increasing their production capabilities to develop chromogenic substrates for ELISA, which are used in combination with horseradish peroxidase enzyme (HRP).

Strategic Acquisitions Help Leverage Opportunities in Sample Preparation Technologies

The horseradish peroxidase market is predicted to surpass the value of US$ 110 Mn by 2030. This is an important revelation, since companies are securing stakes of other companies even amidst the ongoing coronavirus pandemic. For instance, in March 2020, Thermo Fisher Scientific- a U.S. provisioner of reagents, consumables, and scientific instrumentation, announced the acquisition of QIAGEN— a provider of sample and assay technologies for molecular diagnostics to explore opportunities in sample preparation technologies.

In order to achieve increased sensitivity, the technique of chemifluorescence is being used for ELISA reactions. Thus, companies in the horseradish peroxidase market are becoming increasingly aware about this technique and has helped to increase the magnitude of sensitivity in ELISA reactions. They are using photomultiplier tubes with fluorescence detection in order to achieve stability in reactions.

Surge in Usage of Enzymes as Biocatalysts to Drive Horseradish Peroxidase Market

Horseradish peroxidase (HRP) has the ability to catalyze the transfer of two electrons from a substrate to hydrogen peroxide to generate water and an oxidized substrate. Furthermore, HRP-catalyzed reactions of biocatalytical interest include oxidative dehydrogenation, sulfoxidation, and nitrogen oxidation. Hence, biocatalysts such as horseradish peroxidase are utilized in the production of pharmaceuticals and other fine chemicals, which, in turn, fuel the demand for horseradish peroxidase.

TMB (3,3', 5,5”-tetramethylbenzidine) Segment to Dominate Global Market

In terms of substrate, the global horseradish peroxidase market has been classified into ABTS (2,2'-Azinobis [3- ethylbenzothiazoline-6-sulfonic acid]-diammonium salt), OPD (ophenylenediamine dihydrochloride), TMB (3,3',5,5'-tetramethylbenzidine), and others. TMB (3,3', 5,5”-tetramethylbenzidine) is highly sensitive and is often produced to detect signal quickly in ELISA, which helps to identify components such as proteins in the sample quickly. Moreover, it oxidizes rapidly compared to other substrates, resulting in faster color development. This drives the demand for the substrate.

Grade I to be Highly Attractive

Based on grade, the global horseradish peroxidase market has been categorized into grade I, grade II, and grade III. The grade I segment held a major share of the global market in 2020, as biopharmaceutical companies prefer to use high efficiency and good stability grade to conduct research.

Biopharmaceutical Companies to be Highly Lucrative

In terms of end user, the global horseradish peroxidase market has been divided into biopharmaceutical companies, academic & research institutes, and others. Research with horseradish peroxidase is increasing in the biopharmaceutical industry. In combination with a plant hormone, HRP can be utilized in specific enzyme-prodrug therapies. Moreover, rise in research & development activities of biopharmaceutical companies is likely to drive the demand for horseradish peroxidase in the biopharmaceutical companies segment.

North America to Dominate Horseradish Peroxidase Market

In terms of region, the global horseradish peroxidase market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global horseradish peroxidase market in 2020, followed by Europe. North America accounted for a major share of the global horseradish peroxidase market in 2020, primarily due to significant ongoing research & development activities of biopharmaceutical companies, increase in clinical R&D budget to develop new diagnostic tests, and expansion of laboratory test portfolio can be attributed to the region’s dominance.

Some of the prominent players in the Horseradish Peroxidase Market include:

  • Abcam plc
  • Thermo Fisher Scientific, Inc.
  • Bio-Rad Laboratories
  • Merck KGaA,
  • BBI Solutions
  • Takara Bio Company
  • Promega Corporation
  • Faizyme Laboratories
  • F. Hoffmann-La Roche Ltd.
  • TOYOBO Co., Ltd.
  • Oriental Yeast Co., Ltd.
  • GenScript

Segments Covered in the Report

This research report offers market revenue, sales volume, production assessment and prognoses by classifying it on the basis of various aspects. Further, this research study investigates market size, production, consumption and its development trends at global, regional, and country level for the period of 2017 to 2030 and covers subsequent region in its scope:

Global Horseradish Peroxidase Market: Segmentation

  • Horseradish Peroxidase Market, by Substrate
    • ABTS (2,2'-Azinobis [3- ethylbenzothiazoline-6-sulfonic acid]-diammonium salt)
    • OPD (ophenylenediamine dihydrochloride)
    • TMB (3,3',5,5'-tetramethylbenzidine)
    • Others
  • Horseradish Peroxidase Market, by Grade
    • Grade I
    • Grade II
    • Grade III
  • Horseradish Peroxidase Market, by Application
    • Immunoassays
      • ELISA
      • Blot Test
      • Others
    • Biosensors
  • Horseradish Peroxidase Market, by End User
    • Biopharmaceutical Companies
    • Academic & Research Institutes
    • Others

By Geography

North America

  • U.S.
  • Canada


  • Germany
  • France
  • United Kingdom
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Southeast Asia
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Rest of Latin America

Middle East & Africa (MEA)

  • GCC
  • North Africa
  • South Africa
  • Rest of Middle East & Africa

Key Points Covered in Horseradish Peroxidase Market Study:


  • Growth of Horseradish Peroxidase in 2022
  • Market Estimates and Forecasts (2017-2030)
  •  Brand Share and Market Share Analysis
  •  Key Drivers and Restraints Shaping Market Growth
  •  Segment-wise, Country-wise, and Region-wise Analysis
  •  Competition Mapping and Benchmarking
  •  Recommendation on Key Winning Strategies
  •  COVID-19 Impact on Demand for Horseradish Peroxidase and How to Navigate
  •  Key Product Innovations and Regulatory Climate
  •  Horseradish Peroxidase Consumption Analysis
  •  Horseradish Peroxidase Production Analysis
  •  Horseradish Peroxidase and Management

Report Detail

  • Report Code:5994
  • No. of Pages:150+
  • Format:PDF/PPT/Excel

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