Inhalation Anesthesia Market Size, Share, And Trend Analysis By Drug (Sevoflurane, Isoflurane, Desflurane), By Application (Induction, Maintenance), By End-Use (Hospitals, Ambulatory Surgical Centers)- Global Industry Analysis, Share, Growth, Regional Outlook and Forecasts, 2022-2030

The global Inhalation Anesthesia market size was estimated at USD 1.7 billion in 2021 and is expected to surpass around USD 2.9 billion by 2030 and poised to grow at a compound annual growth rate (CAGR) of 9.4% during the forecast period 2022 to 2030.

Key Takeaways:

• By Drug, the U.S. Inhalation Anesthesia market was valued at USD 0.6 Billion in 2021 and expected to witness growth at a CAGR of 8.7% from 2022 to 2030.
• Sevoflurane held the largest market share in 2021 due to the fact that its pharmacokinetics and pharmacodynamics leads to many advantages over other alternate inhaled anesthetic agents available.
• Desflurane, alone or in combination with nitrous oxide or other inhalation anesthetic agents is used in various surgical procedures owing to its rapid onset of action and elimination rate; therefore, driving the segment demand.
• There have been many complications reported with halothane, for instance, halothane-induced hepatitis; therefore, this anesthetic agent has been discontinued in the majority of the western countries.
• North America dominated the market in 2021 due to the high demand for sevoflurane and desflurane in the region. Key companies are also undertaking various strategic initiatives that has led to their high revenue growth in the U.S.
• China is the largest economy in Asia Pacific. It is a country with the maximum population in the world, hence having a large patient pool for surgeries. A large number of surgeries being performed along with the presence of a large patient pool is anticipated to boost the market over the forecast period.

Inhalation anesthetics offer shorter induction period and recovery time along with better efficacy and lesser adverse effects as compared to other alternatives, thus providing better anesthetic effect during surgical procedures. They also provide excellent control over the duration of anesthesia in the patient. Thus, inhalation anesthesia is being preferred over intravenous anesthesia due to these advantages.

Drugs administered through inhalation anesthesia have a quick onset of action even at low dose as compared to intravenous anesthesia. Using inhalation route for administration helps avoid excessive dosage and keeps the patient’s autonomic functions intact. As these drugs are eliminated via lungs, they have lower chances of accumulation in the body. Hence, they result in lower risk of hepatotoxicity. In addition, drugs administered through inhalation route have limited tolerance and addiction level as compared to other alternatives routes.

 With the launch of innovative respiratory products such as AnaConDa (Anaesthetic Conserving Device), administration of inhalation general anesthetic agents such as sevoflurane, isoflurane, & other agents have become easier. Inhalation anesthesia is considered to be the best alternative for patients who are on ventilation for more than 24 hours as it becomes easy to monitor the patient’s health.

Major concern associated with anesthetic gas is that only 5% account for patient use and the rest 95% is released in the atmosphere, which leads to greenhouse effect of these gases. The comparative analysis of sevoflurane, isoflurane, and desflurane based on atmospheric time span and global atmospheric concentrations indicates that desflurane poses a high potential threat for environment.

Report Scope of the Inhalation Anesthesia Market

 Drug Insights

The inhalation anesthesia market is segmented by drug into sevoflurane, desflurane, isoflurane, and halothane. Sevoflurane dominated the inhalation anesthesia market in 2021 because it is potent, rapidly acting, and has faster emergence and recovery as compared to the other drugs available in the market; however, it is more expensive than its alternatives. These factors have led to sevoflurane being the preferred choice of surgeons during surgical procedures for induction and maintenance of anesthesia.

Isoflurane is expected to show the highest growth rate over the forecast period. If fresh gas flow rates are considered, sevoflurane and desflurane cost two to three times more than isoflurane. Hence, isoflurane is the preferred choice for inhalation general anesthesia of anesthesiologists in developing countries owing to the presence of a cost-sensitive patient pool.

The number of manufacturers of halothane is decreasing owing to a decline in demand from hospitals as new agents such as desflurane and sevoflurane are gaining traction. Although halothane is no longer used in clinical practice in North America, it is still extensively used in developing countries and during veterinary surgeries owing to its low cost.

Application Insights

The inhalation anesthesia market is segmented by application into induction and maintenance. The maintenance segment held the largest share in 2021 due to the fact that inhaled anesthetics are more preferred for the maintenance of anesthesia. They allow more precise control of the anesthetic state, which is cost-effective.

Factors influencing induction of anesthesia include a therapeutic index of a drug, Minimum Alveolar Concentration (MAC), potency, patient’s age, rate of metabolism by kidney/liver, compatibility with other drugs, and blood/gas solubility. Inhalation general anesthetic agents have different mechanisms of action in the central nervous system depending on blood and gas solubility and the Minimum Alveolar Concentration (MAC) concentration of different drugs.

Regional Insights

North America dominated the market in 2021 due to the rise in the number of surgeries performed in the U.S. Key players have also gained significant market revenue in the country. Piramal Enterprises Limited, one of the key players in inhalation anesthesia holds the largest market share of sevoflurane and isoflurane in the U.S. Presence of a large number of registered hospitals in the U.S. is also a factor contributing to the high demand for anesthetic drugs in surgeries performed in the country. The total number of U.S. hospitals increased by 61 percent [TD3] from August 2020 to March 2021.

The Asia Pacific is anticipated to witness the fastest growth in the forecast period due to the rising population in the region and subsequent increase in the number of surgical procedures. The growing geriatric population is also a significant factor driving the disease incidence in the region, thereby leading to high demand for inhaled anesthetic drugs. Moreover, in China, sevoflurane and desflurane are widely used in day surgeries owing to advantages such as rapid response and faster recovery.

Some of the prominent players in the Inhalation Anesthesia Market include:

• Halocarbon Products Corporation
• Baxter
• AbbVie
• Lunan Pharmaceutical Group
• Piramal Enterprises Ltd.
• Sandoz International GmbH (Novartis)
• Fresenius Kabi Ag

Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2017 to 2030. For this study, Nova one advisor, Inc. has segmented the global Inhalation Anesthesia market

• Drug

• Sevoflurane
• Desflurane
• Isoflurane
• Halothane
• Application
• Induction
• Maintenance
• End-Use
• Hospitals
• Ambulatory Surgical Centers
• Others

By Geography

North America

• U.S.
• Canada

Europe

• Germany
• France
• United Kingdom
• Rest of Europe

Asia Pacific

• China
• Japan
• India
• Southeast Asia
• Rest of Asia Pacific

Latin America

• Brazil
• Rest of Latin America

Middle East & Africa (MEA)

• GCC
• North Africa
• South Africa
• Rest of Middle East & Africa

Key Points Covered in Inhalation Anesthesia Market Study:

• Growth of Inhalation Anesthesia in 2022
• Market Estimates and Forecasts (2017-2030)
•  Brand Share and Market Share Analysis
•  Key Drivers and Restraints Shaping Market Growth
•  Segment-wise, Country-wise, and Region-wise Analysis
•  Competition Mapping and Benchmarking
•  Recommendation on Key Winning Strategies
•  COVID-19 Impact on Demand for Inhalation Anesthesia and How to Navigate
•  Key Product Innovations and Regulatory Climate
•  Inhalation Anesthesia Consumption Analysis
•  Inhalation Anesthesia Production Analysis
•  Inhalation Anesthesia and Management