The global Liquid Filled Hard Capsules market size was estimated at USD 2.9 billion in 2021 and is expected to surpass around USD 4.8 billion by 2030 and poised to grow at a compound annual growth rate (CAGR) of 7.9% during the forecast period 2022 to 2030.
Overview of Liquid Filled Hard Capsules Market
Liquid filled hard capsule refers to a technology that offers an advanced form of dosage in two different types—hydroxypropyl methylcellulose (HPMC) and gelatin—for multi-particulate, paste, semisolid, and liquid applications. Currently, pharmaceutical companies require various types of dosage forms and technologies with developed customized solutions in order to improve the method of delivery of products to specific areas of the body. Significant applications of liquid filled hard capsules are projected to boost the global liquid filled hard capsules market from 2022 to 2031. Demand for liquid filled hard capsules has increased substantially during the COVID-19 pandemic.
Report Scope of the Liquid Filled Hard Capsules Market
Report Coverage |
Details |
Market Size |
USD 4.8 Billion by 2030 |
Growth Rate |
CAGR of 7.9% from 2022 to 2030 |
Largest Market |
North America |
Fastest Growing Market |
Asia Pacific |
Base Year |
2021 |
Forecast Period |
2022 to 2030 |
Segments Covered |
Size, Application, End-user And Geography, |
Companies Mentioned |
|
Rise in Commercialization of Gelatin Capsule-based Drug Delivery Systems to Drive Global Market
Gelatin capsules are better carriers owing to their capability to encapsulate lipophilic and hydrophilic drugs, and provide protection from degradation. These can act as efficient solubilizing matrices and offer better absorption rates. Gelatin-based immediate-release (IR), extended-release (ER), and delayed-release (DR) formulations perform better than traditional formulations, leading to improved efficacy and better patient compliance. These benefits are resulting in increased acceptance of gelatin-based capsules. This is drives the global liquid filled hard capsules market. Gelatin capsules derived from bovine, porcine, and marine sources have proven beneficial vis-à-vis other natural gelatin based on low toxicity, non-antigenicity, high stability, and high nutritional value parameters. Gelatin capsules exhibit high sustained release of various drugs, owing to their high adsorption capacity and high dispersion ability in the water.
Pharmaceutical Manufacturers Seizing Lucrative Opportunities in Canada
Companies are striving to bring over-the-counter drug manufacturing to North America. CapsCanada, a Lyfe Group company, announced the launch of new liquid filled hard capsule manufacturing service in North America. Liquid filled hard capsule manufacturers are increasing efforts to support the entire manufacturing process, right from formulation and development to full-scale production. Thus, companies are partnering with leading manufacturers of generic and branded drugs in Canada.
In order to increase revenue streams and bolster credibility, manufacturers in the liquid filled hard capsules market are striving to gain the approval of Health Canada, the department of the Government of Canada responsible for national health policy. Liquid filled hard capsule manufacturers in Canada are investing in fully analytical labs that conduct licensing for controlled drugs & substances, including narcotics, and a choice of blister or bottle packaging.
Technological Advancements and Rise in Preference to Drive Medium Capsules Segment
In terms of size, the global liquid filled hard capsules market has been classified into large capsules, medium capsules, and small capsules. The large capsules segment has been split into size 000 and size 00 & 00E. The medium capsules segment has been categorized into size 0 & 0E, size 1, and size 2. The small capsules segment has been segregated into size 3, size 4, and size 5.
The medium capsules segment is likely to witness strong growth due to the increase in usage of medium capsules with advanced technological development.
Liquid Filled Hard Capsules Addressing HPAPI Challenges
Based on application, the global liquid filled hard capsules market has been segmented into drugs, vitamins & mineral, amino acids, peptides & proteins, lipids, and others.
Highly potent or highly toxic active pharmaceutical ingredients (API) require specialized handling. Therefore, companies in the liquid filled hard capsules market are boosting their output capacities in hard-shell liquid fill capsules. Liquid filled capsule products continue to be seen principally as a mechanism to increase bioavailability for poorly soluble drugs. However, they have the potential to address low-dose HPAPI (highly potent API) challenges.
Encapsulated liquid based products offer a proven approach to overcome challenges associated with development, commercial manufacturing, and scale-up of highly potent APIs. These trends are translating into revenue opportunities for companies in the liquid filled hard capsules market. Liquid fill capsules enable the incorporation of an API powder into a liquid formulation, either as a solution or as a suspended solid.
Launch of New Therapeutics to Propel Pharmaceutical & Biopharmaceutical Companies Segment
In terms of end-user, the global liquid filled hard capsules market has been divided into pharmaceutical & biopharmaceutical companies, nutrition supplement manufacturers, and others.
Pharmaceutical & biopharmaceutical companies are increasingly investing in development and launch of new therapeutics. For instance, in 2018, 19 of the 59 novel approved drugs were considered first-in-class, 34 received orphan designation for treating rare diseases, and 24 received fast-track designation, as they are intended for serious conditions with unmet medical needs.
Regional Outlook of Liquid Filled Hard Capsules Market
North America accounted for the largest market share of around 37.8% in terms of revenue in 2021. The region is projected to dominate the global liquid filled hard capsules market during the forecast period. The market in North America is anticipated to grow at a CAGR of 7.9% from 2022 to 2030.
Europe is expected to be the second most lucrative market for liquid filled hard capsules during the forecast period. The region held 28% share of the global market in 2021. The market in the region is likely to grow at a CAGR of 7.8% during the forecast period.
Asia Pacific is anticipated to be the fastest growing market from 2022 to 2030. This can be ascribed to the shift in production bases of several global manufacturers to the region due to high unmet medical needs and untapped growth opportunities. Additionally, rapid economic development in emerging countries such as India and China and increase in healthcare expenditure are projected to augment the liquid filled hard capsules market in Asia Pacific.
Analysis of Key Players in Liquid Filled Hard Capsules Market
The global liquid filled hard capsules market is highly fragmented, with the presence of large number of players. ACG, Altasciences, CapsCanada Corporation, Erawat Pharma Limited, Farmacapsulas S.A., Fine USA Trading, Inc., HealthCaps India Ltd., Lefancaps, Lonza Group, PLx Pharma, Inc., QUALICAPS, and Roxlor are some of the key players operating in the market. These players have adopted various strategies such as geographical expansion, investments in building new manufacturing facilities for liquid filled hard capsules, and mergers & acquisitions to establish a strong distribution network.
Key Developments in Global Liquid Filled Hard Capsules Market
Some of the prominent players in the Liquid Filled Hard Capsules Market include:
Segments Covered in the Report
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2017 to 2030. For this study, Nova one advisor, Inc. has segmented the global Liquid Filled Hard Capsules market
By Geography
North America
Europe
Asia Pacific
Latin America
Middle East & Africa (MEA)
Key Benefits for Stakeholders
Chapter 1. Introduction
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Liquid Filled Hard Capsules Market
4. Market Overview
4.1. Introduction
4.1.1. Size Definition
4.1.2. Industry Evolution / Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Liquid Filled Hard Capsules Market Analysis and Forecast, 2017–2030
4.4.1. Market Revenue Projections (US$ Mn)
4.5. Porter’s Five Force Analysis
5. Key Insights
5.1. U.S. Dietary Supplements Regulatory Overview
5.2. Regulation of Dietary Supplements, by Country
5.3. Un-denatured Type II Collagen Analysis
5.4. Key Industry Events
5.5. COVID-19 Pandemic Impact on Industry (value chain and short / mid / long term impact)
6. Global Liquid Filled Hard Capsules Market Analysis and Forecast, by Size
6.1. Introduction & Definition
6.2. Key Findings / Developments
6.3. Market Value & Volume Forecast, by Size, 2017–2030
6.3.1. Large Capsules
6.3.1.1. Size 000
6.3.1.2. Size 00 & 00E
6.3.2. Medium Capsules
6.3.2.1. Size 0 & 0E
6.3.2.2. Size 1
6.3.2.3. Size 2
6.3.3. Small Capsules
6.3.3.1. Size 3
6.3.3.2. Size 4
6.3.3.3. Size 5
6.4. Market Attractiveness Analysis, by Size
7. Global Liquid Filled Hard Capsules Market Analysis and Forecast, by Application
7.1. Introduction & Definition
7.2. Key Findings / Developments
7.3. Market Value & Volume Forecast, by Application, 2017–2030
7.3.1. Drugs
7.3.2. Vitamins & Mineral
7.3.3. Amino Acids, Peptides, and Proteins
7.3.4. Lipids
7.3.5. Others
7.4. Market Attractiveness Analysis, by Application
8. Global Liquid Filled Hard Capsules Market Analysis and Forecast, by End-user
8.1. Introduction & Definition
8.2. Key Findings / Developments
8.3. Market Value & Volume Forecast, by End-user, 2017–2030
8.3.1. Pharmaceutical & Biopharmaceutical Companies
8.3.2. Nutrition Supplement Manufacturers
8.3.3. Others
8.4. Market Attractiveness Analysis, by End-user/p>
9. Global Liquid Filled Hard Capsules Market Analysis and Forecast, by Region
9.1. Key Findings
9.2. Market Value & Volume Forecast, by Region
9.2.1. North America
9.2.2. Europe
9.2.3. Asia
9.2.4. Latin America
9.2.5. Middle East & Africa
9.3. Market Attractiveness Analysis, by Region
10. North America Liquid Filled Hard Capsules Market Analysis and Forecast
10.1. Introduction
10.1.1. Key Findings
10.2. Market Value & Volume Forecast, by Size, 2017–2030
10.2.1. Large Capsules
10.2.1.1. Size 000
10.2.1.2. Size 00 & 00E
10.2.2. Medium Capsules
10.2.2.1. Size 0 & 0E
10.2.2.2. Size 1
10.2.2.3. Size 2
10.2.3. Small Capsules
10.2.3.1. Size 3
10.2.3.2. Size 4
10.2.3.3. Size 5
10.3. Market Value & Volume Forecast, by Application, 2017–2030
10.3.1. Drugs
10.3.2. Vitamins & Mineral
10.3.3. Amino Acids, Peptides, and Proteins
10.3.4. Lipids
10.3.5. Others
10.4. Market Value & Volume Forecast, by End-user, 2017–2030
10.4.1. Pharmaceutical & Biopharmaceutical Companies
10.4.2. Nutrition Supplement Manufacturers
10.4.3. Others
10.5. Market Value & Volume Forecast, by Country, 2017–2030
10.5.1. U.S.
10.5.2. Canada
10.6. Market Attractiveness Analysis
10.6.1. by Size
10.6.2. by Application
10.6.3. by End-user
10.6.4. by Country
11. Europe Liquid Filled Hard Capsules Market Analysis and Forecast
11.1. Introduction
11.1.1. Key Findings
11.2. Market Value & Volume Forecast, by Size, 2017–2030
11.2.1. Large Capsules
11.2.1.1. Size 000
11.2.1.2. Size 00 & 00E
11.2.2. Medium Capsules
11.2.2.1. Size 0 & 0E
11.2.2.2. Size 1
11.2.2.3. Size 2
11.2.3. Small Capsules
11.2.3.1. Size 3
11.2.3.2. Size 4
11.2.3.3. Size 5
11.3. Market Value & Volume Forecast, by Application, 2017–2030
11.3.1. Drugs
11.3.2. Vitamins & Mineral
11.3.3. Amino Acids, Peptides, and Proteins
11.3.4. Lipids
11.3.5. Others
11.4. Market Value & Volume Forecast, by End-user, 2017–2030
11.4.1. Pharmaceutical & Biopharmaceutical Companies
11.4.2. Nutrition Supplement Manufacturers
11.4.3. Others
11.5. Market Value & Volume Forecast, by Country/Sub-region, 2017–2030
11.5.1. Germany
11.5.2. U.K.
11.5.3. France
11.5.4. Spain
11.5.5. Italy
11.5.6. Rest of Europe
11.6. Market Attractiveness Analysis
11.6.1. by Size
11.6.2. by Application
11.6.3. by End-user
11.6.4. by Country/Sub-region
12. Asia Liquid Filled Hard Capsules Market Analysis and Forecast
12.1. Introduction
12.1.1. Key Findings
12.2. Market Value & Volume Forecast, by Size, 2017–2030
12.2.1. Large Capsules
12.2.1.1. Size 000
12.2.1.2. Size 00 & 00E
12.2.2. Medium Capsules
12.2.2.1. Size 0 & 0E
12.2.2.2. Size 1
12.2.2.3. Size 2
12.2.3. Small Capsules
12.2.3.1. Size 3
12.2.3.2. Size 4
12.2.3.3. Size 5
12.3. Market Value & Volume Forecast, by Application, 2017–2030
12.3.1. Drugs
12.3.2. Vitamins & Mineral
12.3.3. Amino Acids, Peptides, and Proteins
12.3.4. Lipids
12.3.5. Others
12.4. Market Value & Volume Forecast, by End-user, 2017–2030
12.4.1. Pharmaceutical & Biopharmaceutical Companies
12.4.2. Nutrition Supplement Manufacturers
12.4.3. Others
12.5. Market Value & Volume Forecast, by Country/Sub-region, 2017–2030
12.5.1. Japan
12.5.2. China
12.5.3. India
12.5.4. Australia & New Zealand
12.5.5. Rest of Asia
12.6. Market Attractiveness Analysis
12.6.1. by Size
12.6.2. by Application
12.6.3. by End-user
12.6.4. by Country/Sub-region
13. Latin America Liquid Filled Hard Capsules Market Analysis and Forecast
13.1. Introduction
13.1.1. Key Findings
13.2. Market Value & Volume Forecast, by Size, 2017–2030
13.2.1. Large Capsules
13.2.1.1. Size 000
13.2.1.2. Size 00 & 00E
13.2.2. Medium Capsules
13.2.2.1. Size 0 & 0E
13.2.2.2. Size 1
13.2.2.3. Size 2
13.2.3. Small Capsules
13.2.3.1. Size 3
13.2.3.2. Size 4
13.2.3.3. Size 5
13.3. Market Value & Volume Forecast, by Application, 2017–2030
13.3.1. Drugs
13.3.2. Vitamins & Mineral
13.3.3. Amino Acids, Peptides, and Proteins
13.3.4. Lipids
13.3.5. Others
13.4. Market Value & Volume Forecast, by End-user, 2017–2030
13.4.1. Pharmaceutical & Biopharmaceutical Companies
13.4.2. Nutrition Supplement Manufacturers
13.4.3. Others
13.5. Market Value & Volume Forecast, by Country/Sub-region, 2017–2030
13.5.1. Brazil
13.5.2. Mexico
13.5.3. Rest of Latin America
13.6. Market Attractiveness Analysis
13.6.1. by Size
13.6.2. by Application
13.6.3. by End-user
13.6.4. by Country/Sub-region
14. Middle East & Africa Liquid Filled Hard Capsules Market Analysis and Forecast
14.1. Introduction
14.1.1. Key Findings
14.2. Market Value & Volume Forecast, by Size, 2017–2030
14.2.1. Large Capsules
14.2.1.1. Size 000
14.2.1.2. Size 00 & 00E
14.2.2. Medium Capsules
14.2.2.1. Size 0 & 0E
14.2.2.2. Size 1
14.2.2.3. Size 2
14.2.3. Small Capsules
14.2.3.1. Size 3
14.2.3.2. Size 4
14.2.3.3. Size 5
14.3. Market Value & Volume Forecast, by Application, 2017–2030
14.3.1. Drugs
14.3.2. Vitamins & Mineral
14.3.3. Amino Acids, Peptides, and Proteins
14.3.4. Lipids
14.3.5. Others
14.4. Market Value & Volume Forecast, by End-user, 2017–2030
14.4.1. Pharmaceutical & Biopharmaceutical Companies
14.4.2. Nutrition Supplement Manufacturers
14.4.3. Others
14.5. Market Value & Volume Forecast, by Country/Sub-region, 2017–2030
14.5.1. GCC Countries
14.5.2. South Africa
14.5.3. Rest of Middle East & Africa
14.6. Market Attractiveness Analysis
14.6.1. by Size
14.6.2. by Application
14.6.3. by End-user
14.6.4. by Country/Sub-region
15. Competition Landscape
15.1. Market Player - Competition Matrix (by tier and size of companies)
15.2. Market Share Analysis, by Company, 2021
15.3. Company Profiles
15.3.1. ACG
15.3.1.1. Company Description
15.3.1.2. Business Overview
15.3.1.3. Strategic Overview
15.3.1.4. SWOT Analysis
15.3.2. Altasciences
15.3.2.1. Company Description
15.3.2.2. Business Overview
15.3.2.3. Strategic Overview
15.3.2.4. SWOT Analysis
15.3.3. CapsCanada Corporation
15.3.3.1. Company Description
15.3.3.2. Business Overview
15.3.3.3. Strategic Overview
15.3.3.4. SWOT Analysis
15.3.4. Erawat Pharma Limited
15.3.4.1. Company Description
15.3.4.2. Business Overview
15.3.4.3. Strategic Overview
15.3.4.4. SWOT Analysis
15.3.5. Farmacapsulas S.A.
15.3.5.1. Company Description
15.3.5.2. Business Overview
15.3.5.3. Strategic Overview
15.3.5.4. SWOT Analysis
15.3.6. Fine USA Trading, Inc.
15.3.6.1. Company Description
15.3.6.2. Business Overview
15.3.6.3. Strategic Overview
15.3.6.4. SWOT Analysis
15.3.7. HealthCaps India Ltd.
15.3.7.1. Company Description
15.3.7.2. Business Overview
15.3.7.3. Strategic Overview
15.3.7.4. SWOT Analysis
15.3.8. Lefancaps
15.3.8.1. Company Description
15.3.8.2. Business Overview
15.3.8.3. Strategic Overview
15.3.8.4. SWOT Analysis
15.3.9. PLx Pharma, Inc.
15.3.9.1. Company Description
15.3.9.2. Financial Overview
15.3.9.3. Business Overview
15.3.9.4. Strategic Overview
15.3.9.5.SWOT Analysis
15.3.10. Lonza Group
15.3.10.1. Company Description
15.3.10.2. Financial Overview
15.3.10.3. Business Overview
15.3.10.4. Strategic Overview
15.3.10.5. SWOT Analysis
15.3.11. QUALICAPS
15.3.11.1. Company Description
15.3.11.2. Business Overview
15.3.11.3 .Strategic Overview
15.3.11.3. SWOT Analysis
15.3.12. Roxlor
15.3.12.1. Company Description
15.3.12.2. Business Overview
15.3.12.3. Strategic Overview
15.3.12.4. SWOT Analysis