Single-use Bioprocessing Market Size, Share & Trends Analysis Report By Product (Simple & Peripheral Elements, Apparatus & Plants, Work Equipment), By Workflow (Upstream, Downstream), By End-use, By Region, And Segment - Global Industry Analysis, Size, Share, Growth, Trends, Regional Outlook, and Forecast 2024-2033

The global single-use bioprocessing market size was estimated at USD 28.45 billion in 2023 and is projected to hit around USD 128.24 billion by 2033, growing at a CAGR of 16.25% during the forecast period from 2024 to 2033.

Single-use Bioprocessing Market Size, 2024 to 2033

Key Takeaways:

  • North America held the largest revenue share of more than 34.45% in 2023.
  • The Asia Pacific region is expected to grow at the fastest rate over the forecast period.
  • The simple & peripheral elements segment recorded the largest market share of 49.61% in 2023.
  • The apparatus & plants segment is projected to grow at a rapid CAGR over the forecast period.
  • The upstream bioprocessing segment held the largest market share in 2023.
  • The fermentation segment is expected to register significant CAGR over the forecast period.
  • Biopharmaceutical manufacturers dominated the market and accounted for the highest share in 2023.
  • Academic & clinical research institutes are expected to grow at the fastest CAGR during 2024-2033.

Single-use Bioprocessing Market Growth

The adoption of single-use bioprocessing technology is driven by the growing demand for biopharmaceuticals over the past few years, along with an increase in investments for the development of biologics, such as monoclonal antibodies, vaccines, recombinant proteins, and others. Furthermore, benefits pertaining to the use of single-use technology, such as significant reduction in costs and time required for operations & facility construction have supported the implementation of single-use systems in the bioprocessing sector.

The COVID-19 pandemic has generated new growth opportunities for key stakeholders in the industry. Key biopharmaceutical players can leverage the opportunity by expanding their COVID-19-related product offerings by scaling up their production facilities with the implementation of single-use bioprocessing equipment. A significant number of biopharmaceutical companies are actively involved in the development & production of COVID-19 vaccines. These programs are majorly based on single-use technologies as these systems are flexible, cost-effective, and reduce the risk of cross-contamination.

Such an ongoing and continuous increase in the adoption of these bioprocessing systems due to the COVID-19 pandemic is anticipated to drive industry growth. The commercial success of biopharmaceuticals has led single-use manufacturers to expand their production facilities globally. Capacity expansion projects have been a part of many manufacturers’ multi-year plans, to leverage a global reach and a broader customer base. For instance, in December 2020, Merck KGaA invested over USD 42 million to broaden its existing manufacturing facilities in Danvers, Massachusetts, and Jaffrey, New Hampshire, U.S.

This expansion was aimed at enhancing the company’s single-use assembly operations along with other product portfolios. Furthermore, with the rising focus on the development of regenerative medicine, such as cell and gene therapies, increased success of clinical trials, and enhanced rate of regulatory approvals, demand for commercialization of these products is expected to grow in the near future. In addition, owing to the increasing outsourcing activities in biopharmaceutical manufacturing, CMOs are adopting single-use systems for maintaining highly dynamic and frequently changing product portfolios.

Consequently, the extensive implementation of single-use systems in CMOs across the globe is likely to boost industry growth. For instance, in July 2021, Pall Corp. signed a contract with Exothera S.A., a CDMO, to establish a manufacturing space using Allegro STR single-use bioreactors and other technologies. Although innovations in single-use technology are the current trend for the bioprocessing industry, the technology has still not completely displaced stainless steel reusable systems. High-volume biopharmaceutical product manufacturers continue to fixate on the multi-use system due to their feasibility at large scales. This represents a significant challenge for the industry's growth.

Single-use Bioprocessing Market Report Scope

Report Attribute Details
Market Size in 2024 USD 33.07 Billion
Market Size by 2033 USD 128.24 Billion
Growth Rate From 2024 to 2033 CAGR of 16.25%
Base Year 2023
Forecast Period 2024 to 2033
Segments Covered Product, workflow, end-use, region
Market Analysis (Terms Used) Value (US$ Million/Billion) or (Volume/Units)
Report Coverage Revenue forecast, company ranking, competitive landscape, growth factors, and trends
Key Companies Profiled Sartorius AG; Danaher Corporation; Thermo Fisher Scientific, Inc.; Merck KGaA; Avantor, Inc; Eppendorf SE; Corning Incorporated; Lonza; PBS Biotech, Inc.; Meissner Filtration Products, Inc.

 

Product Insights

The simple & peripheral elements segment recorded the largest market share of 49.61% in 2023 due to continuous innovations in these products and increasing prominence of bioprocessing operations in overall manufacturing process. Tubing, filters, connectors, and transfer systems held a majority share within simple & peripheral elements as tubing and connectors are provided by most single-use suppliers in a compatible format with single-use bags, bioreactors, or other single-use bioprocessing apparatus. For instance, Thermo Fisher Scientific, Inc. offers customization options to add tubing and connectors to its bioprocessing container bags and other bioprocessing equipment.These factors are expected to drive the segment.

The apparatus & plants segment is projected to grow at a rapid CAGR over the forecast period due to its significant penetration in the bioprocessing space majorly driven by a variety of single-use bioreactors. For instance, single-use bioreactors are available from a working volume range of 15 mL and 250 mL, such as the Ambr 15 and 250 sold by Sartorius AG, to a working volume of 6000 L, such as the CSR 7500 SUB sold by ABEC. This allows the end-users to easily scale products right from the stage of clone selection and benchtop production to harvesting high-volume yields of biologics. As a result, the availability of a broad range of options for apparatus & plants for bioprocessing is anticipated to drive the segment.

Workflow Insights

The upstream bioprocessing segment held the largest market share in 2023. This can be attributed to the continuous developments and advancements in technologies for upstream bioprocessing. For instance, advanced products, such as Ambr 15 micro-bioreactor system by Sartorius AG, are offering high-throughput upstream process development as well as efficient cell culture processing and media & feed optimization with automated experimental setup and sampling. These solutions can reduce the time taken for upstream bioprocessing operations and are anticipated to boost segment growth.

The fermentation segment is expected to register significant CAGR over the forecast period. The growth can be attributed to the launch of several innovative fermentation offerings that provide optimum conditions for bioprocessing reactions. For instance, the HyPerforma Enhanced S.U.F by Thermo Fisher Scientific, Inc. delivers optimal oxygen mass transfers and temperature control to the culture by increasing the turbine impellers and cooling jacket surface areas, respectively. Furthermore, companies like Cytiva are also involved in bringing single-use fermentation solutions for their end-users, such as the Xcellerex XDR MO, a stirred tank system with powerful mixing, efficient temperature control, and high oxygen transfer capacities for microbial cell culture. Significant innovations like these are likely to aid in revenue generation in this segment.

End-use Insights

Biopharmaceutical manufacturers dominated the market and accounted for the highest share in 2023. An increase in the commercial success of biologics in recent years and a rise in contract manufacturing/research services have led to the high growth of the segment. CROs and CMOs can offer several benefits in bioprocessing operations, such as scalability, flexibility, decreased internal infrastructure requirements, and dedicated supply channels. These advantages are fueling the adoption of contract services and are anticipated to positively affect the industry growth in the near future.

Academic & clinical research institutes are expected to grow at the fastest CAGR during 2024-2033.The availability of benchtop scale bioprocessing equipment and technological progress in single-use systems has accelerated the adoption of such technologies in academic and research institutes. For instance, institutes like the NIBRT (National Institute for Bioprocessing Research), in Ireland offer contract research services for biologics, while also conducting workshops and training for single-use technologies. Furthermore, the involvement of academic institutes and scientific communities in developing new biologics, such as cell & gene therapies and vector production, is likely to increase the implementation of single-use systems due to its cost reduction and flexibility benefits.

Regional Insights

North America held the largest revenue share of more than 34.45% in 2023, which can be attributed to the presence of an established pharmaceutical and biomanufacturing industry in the region as well as a high extent of R&D activities. Similarly, the demand for single-use bioprocessing equipment is also driven by an increasing focus on vaccine production to aid in disease prevention measures in the region. Moreover, the presence of the Bio-process System Alliance (BPSA) in North America, which aims at advancing the adoption of single-use technologies, is expected to further drive the sales of disposable systems in the region.

The Asia Pacific region is expected to grow at the fastest rate over the forecast period. The region’s growing bioprocessing market has resulted in multiple investments from several global companies. These investments assist in serving the key companies to create a regional presence and take advantage of the untapped avenues. Furthermore, the increasing interest of contract service providers to develop their base in the Asia Pacific, coupled with the trend of implementation of disposables in CMOs, acts as a catalyst for continued investments by local as well as global companies. For instance, in September 2021, Singapore witnessed the expansion of Lonza’s drug development facility. The CDMO enhanced its capacity to support the growing manufacturing needs in the region.

In China, the expansion of biopharmaceuticals market is driving the single-use bioprocessing market. Several international companies have expanded their manufacturing footprint in this region by forming mutually beneficial partnerships with China-based entities. Moreover, the primary focus of the country is on the development of affordable biosimilars of Western novel biotherapeutics for its domestic market, which is anticipated to positively influence market growth in the coming years.

Recent Developments

  • In January 2024, CDMO AGC Biologics announced a growth strategy to develop pharmaceutical manufacturing capabilities in the Asia region through the expansion of their mammalian cell culture, mRNA and cell therapy facility in Japan. This development is aimed to support the global demand for biologics and advanced therapy medicinal products.
  • In September 2023, Getinge launched a single-use bioreactor named the AppliFlex ST GMP. The new product is available in different sizes and provides a comprehensive cGMP manufacturing solution for mRNA production and cell and gene therapies.
  • In April 2023, Merck KGaA launched Ultimus, a single-use process container film, to provide superior strength & leak resistance for single-use assemblies.
  • In April 2023, Cytiva introduced the X-platform bioreactors that simplifies the upstream bioprocessing operations for the production of monoclonal antibodies (mAbs), protein-based drugs and cell and gene therapies.

Key Single-use Bioprocessing Companies:

The following are the leading companies in the single-use bioprocessing market. These companies collectively hold the largest market share and dictate industry trends. Financials, strategy maps & products of these single-use bioprocessing companies are analyzed to map the supply network.

  • Sartorius AG
  • Danaher
  • Thermo Fisher Scientific, Inc.
  • Merck KGaA
  • Avantor, Inc.
  • Eppendorf SE
  • Corning Incorporated
  • Lonza
  • PBS Biotech, Inc.
  • Meissner Filtration Products, Inc.

Segments Covered in the Report

This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Nova one advisor, Inc. has segmented the Single-use Bioprocessing market.

By Product 

  • Simple & Peripheral Elements
      • Tubing, Filters, Connectors, & Transfer Systems
      • Bags
      • Sampling Systems
      • Probes & Sensors
        • pH Sensor
        • Oxygen Sensor
        • Pressure Sensors
        • Temperature Sensors
        • Conductivity Sensors
        • Flow Sensors
        • Others
      • Others
  • Apparatus & Plants
    • Bioreactors
      • Upto 1000L
      • Above 1000L to 2000L
      • Above 2000L
    • Mixing, Storage, & Filling Systems
    • Filtration System
    • Chromatography Systems
    • Pumps
    • Others
  • Work Equipment
    • Cell Culture System
    • Syringes
    • Others

By Workflow 

  • Upstream Bioprocessing
  • Fermentation
  • Downstream Bioprocessing

By By End-use 

  • Biopharmaceutical Manufacturers
    • CMOs & CROs
    • In-house Manufacturers
  • Academic & Clinical Research Institutes

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America

Chapter 1. Methodology and Scope
                      1.1. Market Segmentation and Scope
                          1.1.1. Product Segment
                          1.1.2. Workflow Segment
                          1.1.3. End Use Segment
                      1.2. Regional Scope
                      1.3. Estimates and Forecast Timeline
                      1.4. Research Methodology
                      1.5. Information Procurement
                          1.5.1. Purchased Database
                          1.5.2. nova one advisor Internal Database
                          1.5.3. Primary Research
                      1.6. Information or Data Analysis:
                          1.6.1. Data Analysis Models
                      1.7. Market Formulation & Validation
                      1.8. Model Details
                          1.8.1. Commodity Flow Analysis
                      1.9. List of Secondary Sources
                      1.10. List of Abbreviations
                      1.11. Objective
                          1.11.1. Objective 1
                          1.11.2. Objective2
Chapter 2. Executive Summary
                      2.1. Market Outlook
                      2.2. Segment Snapshot
                      2.3. Competitive Landscape Snapshot
Chapter 3. Market Variables, Trends, & Scope
                      3.1. Market Lineage Outlook
                          3.1.1. Parent Market Outlook
                          3.1.2. Related/Ancillary Market Outlook
                      3.2. Market Dynamics
                          3.2.1. Market Driver Analysis
                              3.2.1.1. Several advantages associated with implementation of single use technology in bio-manufacturing process
                              3.2.1.2. Increasing investments in expansion of cGMP manufacturing
                              3.2.1.3. Widespread adoption of single use technology by CMOs
                          3.2.2. Market Restraint Analysis
                              3.2.2.1. Concerns due to leachable and extractable
                              3.2.2.2. Limited adoption of single use technology in downstream process
                          3.2.3. Market Challenge Analysis
                              3.2.3.1. Delay in the delivery speed and supply chain of customized products
                              3.2.3.2. Restraints with scalability of single-use operations
                              3.2.3.3. Vast availability of multi-use systems
                          3.2.4. Market Opportunity Analysis
                              3.2.4.1. Developing technologies for downstream adoption
                              3.2.4.2. CMO-outsourcing to focus on the new product development
                      3.3. Industry Analysis Tools
                          3.3.1. Porter’s Five Forces Analysis
                          3.3.2. PESTEL Analysis
                          3.3.3. COVID-19 Impact Analysis
                          3.3.4. Average Pricing Analysis
Chapter 4. Product Business Analysis
                      4.1. Single-use Bioprocessing Market: Product Movement Analysis
                      4.2. Simple & Peripheral Elements
                          4.2.1. Simple & peripheral elements market estimates and forecasts, 2021 - 2033
                          4.2.2. Tubing, Filters, Connectors, & Transfer Systems
                              4.2.2.1. Tubing, Filters, Connectors, & Transfer Systems market estimates and forecasts, 2021 - 2033
                          4.2.3. Bags
                              4.2.3.1. Bags market estimates and forecasts, 2021 - 2033
                          4.2.4. Sampling Systems
                              4.2.4.1. Sampling systems market estimates and forecasts, 2021 - 2033
                          4.2.5. Probes & Sensors
                              4.2.5.1. Probes & sensors market estimates and forecasts, 2021 - 2033
                              4.2.5.2. pH Sensor
                                  4.2.5.2.1. pH sensor market estimates and forecasts, 2021 - 2033
                              4.2.5.3. Oxygen Sensor
                                  4.2.5.3.1. Oxygen sensor market estimates and forecasts, 2021 - 2033
                              4.2.5.4. Pressure Sensors
                                  4.2.5.4.1. Pressure sensors market estimates and forecasts, 2021 - 2033
                              4.2.5.5. Temperature Sensors
                                  4.2.5.5.1. Temperature sensors market estimates and forecasts, 2021 - 2033
                              4.2.5.6. Conductivity Sensor
                                  4.2.5.6.1. Conductivity sensor market estimates and forecasts, 2021 - 2033
                              4.2.5.7. Flow Sensors
                                  4.2.5.7.1. Flow sensors market estimates and forecasts, 2021 - 2033
                              4.2.5.8. Others
                                  4.2.5.8.1. Others market estimates and forecasts, 2021 - 2033
                          4.2.6. Others
                              4.2.6.1. Others market estimates and forecasts, 2021 - 2033
                      4.3. Apparatus & Plants
                          4.3.1. Apparatus & plants market estimates and forecasts, 2021 - 2033
                          4.3.2. Bioreactors
                              4.3.2.1. Bioreactors market estimates and forecasts, 2021 - 2033
                              4.3.2.2. Upto 1000L
                                  4.3.2.2.1. Upto 1000L market estimates and forecasts, 2021 - 2033
                              4.3.2.3. Above 1000L to 2000L
                                  4.3.2.3.1. Above 1000L to 2000L market estimates and forecasts, 2021 - 2033
                              4.3.2.4. Above 2000L
                                  4.3.2.4.1. Above 2000L market estimates and forecasts, 2021 - 2033
                          4.3.3. Mixing, Storage, & Filling Systems
                              4.3.3.1. Mixing, storage, & filling systems market estimates and forecasts, 2021 - 2033
                          4.3.4. Filtration System
                              4.3.4.1. Filtration system market estimates and forecasts, 2021 - 2033
                          4.3.5. Chromatography Systems
                              4.3.5.1. Chromatography systems market estimates and forecasts, 2021 - 2033
                          4.3.6. Pumps
                              4.3.6.1. Pumps market estimates and forecasts, 2021 - 2033
                          4.3.7. Others
                              4.3.7.1. Others market estimates and forecasts, 2021 - 2033
                      4.4. Work Equipment
                          4.4.1. Work equipment market estimates and forecasts, 2021 - 2033
                          4.4.2. Cell Culture System
                              4.4.2.1. Cell culture system market estimates and forecasts, 2021 - 2033
                          4.4.3. Syringes
                              4.4.3.1. Syringes market estimates and forecasts, 2021 - 2033
                          4.4.4. Others
                              4.4.4.1. Others market estimates and forecasts, 2021 - 2033
Chapter 5. Workflow Business Analysis
                      5.1. Single-use Bioprocessing Market: Workflow Movement Analysis
                      5.2. Upstream Bioprocessing
                          5.2.1. Upstream bioprocessing market estimates and forecasts, 2021 - 2033
                      5.3. Fermentation
                          5.3.1. Fermentation market estimates and forecasts, 2021 - 2033
                      5.4. Downstream Bioprocessing
                          5.4.1. Downstream bioprocessing market estimates and forecasts, 2021 - 2033
Chapter 6. End Use Business Analysis
                      6.1. Single-use Bioprocessing Market: End Use Movement Analysis
                      6.2. Biopharmaceutical Manufacturers
                          6.2.1. Biopharmaceutical manufacturers market estimates and forecasts, 2021 - 2033
                          6.2.2. CMOs & CROs
                              6.2.2.1. CMOs & CROs market estimates and forecasts, 2021 - 2033
                          6.2.3. In-house Manufacturers
                              6.2.3.1. In-house manufacturers market estimates and forecasts, 2021 - 2033
                      6.3. Academic & Clinical Research Institutes
                          6.3.1. Academic & clinical research institutes market estimates and forecasts, 2021 - 2033
Chapter 7. Regional Business Analysis
                      7.1. Single-use Bioprocessing Share By Region, 2023 & 2030
                      7.2. North America
                          7.2.1. North America Single-use Bioprocessing, 2021 - 2033
                          7.2.2. U.S.
                              7.2.2.1. Key Country Dynamics
                              7.2.2.2. Competitive Scenario
                              7.2.2.3. U.S. Single-use Bioprocessing, 2021 - 2033
                          7.2.3. Canada
                              7.2.3.1. Key Country Dynamics
                              7.2.3.2. Competitive Scenario
                              7.2.3.3. Canada Single-use Bioprocessing, 2021 - 2033
                      7.3. Europe
                          7.3.1. Europe Single-use Bioprocessing, 2021 - 2033
                          7.3.2. UK
                              7.3.2.1. Key Country Dynamics
                              7.3.2.2. Competitive Scenario
                              7.3.2.3. UK Single-use Bioprocessing, 2021 - 2033
                          7.3.3. Germany
                              7.3.3.1. Key Country Dynamics
                              7.3.3.2. Competitive Scenario
                              7.3.3.3. Germany Single-use Bioprocessing, 2021 - 2033
                          7.3.4. France
                              7.3.4.1. Key Country Dynamics
                              7.3.4.2. Competitive Scenario
                              7.3.4.3. France Single-use Bioprocessing, 2021 - 2033
                          7.3.5. Italy
                              7.3.5.1. Key Country Dynamics
                              7.3.5.2. Competitive Scenario
                              7.3.5.3. Italy Single-use Bioprocessing, 2021 - 2033
                          7.3.6. Spain
                              7.3.6.1. Key Country Dynamics
                              7.3.6.2. Competitive Scenario
                              7.3.6.3. Spain Single-use Bioprocessing, 2021 - 2033
                          7.3.7. Denmark
                              7.3.7.1. Key Country Dynamics
                              7.3.7.2. Competitive Scenario
                              7.3.7.3. Denmark Single-use Bioprocessing, 2021 - 2033
                          7.3.8. Sweden
                              7.3.8.1. Key Country Dynamics
                              7.3.8.2. Competitive Scenario
                              7.3.8.3. Sweden Single-use Bioprocessing, 2021 - 2033
                          7.3.9. Norway
                              7.3.9.1. Key Country Dynamics
                              7.3.9.2. Competitive Scenario
                              7.3.9.3. Norway Single-use Bioprocessing, 2021 - 2033
                      7.4. Asia Pacific
                          7.4.1. Asia Pacific Single-use Bioprocessing, 2021 - 2033
                          7.4.2. Japan
                              7.4.2.1. Key Country Dynamics
                              7.4.2.2. Competitive Scenario
                              7.4.2.3. Japan Single-use Bioprocessing, 2021 - 2033
                          7.4.3. China
                              7.4.3.1. Key Country Dynamics
                              7.4.3.2. Competitive Scenario
                              7.4.3.3. China Single-use Bioprocessing, 2021 - 2033
                          7.4.4. India
                              7.4.4.1. Key Country Dynamics
                              7.4.4.2. Competitive Scenario
                              7.4.4.3. India Single-use Bioprocessing, 2021 - 2033
                          7.4.5. Australia
                              7.4.5.1. Key Country Dynamics
                              7.4.5.2. Competitive Scenario
                              7.4.5.3. Australia Single-use Bioprocessing, 2021 - 2033
                          7.4.6. Thailand
                              7.4.6.1. Key Country Dynamics
                              7.4.6.2. Competitive Scenario
                              7.4.6.3. Thailand Single-use Bioprocessing, 2021 - 2033
                          7.4.7. South Korea
                              7.4.7.1. Key Country Dynamics
                              7.4.7.2. Competitive Scenario
                              7.4.7.3. South Korea Single-use Bioprocessing, 2021 - 2033
                      7.5. Latin America
                          7.5.1. Latin America Single-use Bioprocessing, 2021 - 2033
                          7.5.2. Brazil
                              7.5.2.1. Key Country Dynamics
                              7.5.2.2. Competitive Scenario
                              7.5.2.3. Brazil Single-use Bioprocessing, 2021 - 2033
                          7.5.3. Mexico
                              7.5.3.1. Key Country Dynamics
                              7.5.3.2. Competitive Scenario
                              7.5.3.3. Mexico Single-use Bioprocessing, 2021 - 2033
                          7.5.4. Argentina
                              7.5.4.1. Key Country Dynamics
                              7.5.4.2. Competitive Scenario
                              7.5.4.3. Argentina Single-use Bioprocessing, 2021 - 2033
                      7.6. MEA
                          7.6.1. MEA Single-use Bioprocessing, 2021 - 2033
                          7.6.2. South Africa
                              7.6.2.1. Key Country Dynamics
                              7.6.2.2. Competitive Scenario
                              7.6.2.3. South Africa Single-use Bioprocessing, 2021 - 2033
                          7.6.3. Saudi Arabia
                              7.6.3.1. Key Country Dynamics
                              7.6.3.2. Competitive Scenario
                              7.6.3.3. Saudi Arabia Single-use Bioprocessing, 2021 - 2033
                          7.6.4. UAE
                              7.6.4.1. Key Country Dynamics
                              7.6.4.2. Competitive Scenario
                              7.6.4.3. UAE Single-use Bioprocessing, 2021 - 2033
                          7.6.5. Kuwait
                              7.6.5.1. Key Country Dynamics
                              7.6.5.2. Competitive Scenario
                              7.6.5.3. Kuwait Single-use Bioprocessing, 2021 - 2033
Chapter 8. Competitive Landscape
                      8.1. Company Categorization
                      8.2. Strategy Mapping
                      8.3. Company Market Position Analysis, 2023
                      8.4. Company Profiles/Listing
                          8.4.1. Sartorius AG
                              8.4.1.1. Overview
                              8.4.1.2. Financial Performance
                              8.4.1.3. Product Benchmarking
                              8.4.1.4. Strategic Initiatives
                          8.4.2. Thermo Fisher Scientific, Inc.
                              8.4.2.1. Overview
                              8.4.2.2. Financial Performance
                              8.4.2.3. Product Benchmarking
                              8.4.2.4. Strategic Initiatives
                          8.4.3. Danaher
                              8.4.3.1. Overview
                              8.4.3.2. Financial Performance
                              8.4.3.3. Product Benchmarking
                              8.4.3.4. Strategic Initiatives
                          8.4.4. Merck KGaA
                              8.4.4.1. Overview
                              8.4.4.2. Financial Performance
                              8.4.4.3. Product Benchmarking
                              8.4.4.4. Strategic Initiatives
                          8.4.5. Avantor Inc.
                              8.4.5.1. Overview
                              8.4.5.2. Financial Performance
                              8.4.5.3. Product Benchmarking
                              8.4.5.4. Strategic Initiatives
                          8.4.6. Eppendorf SE
                              8.4.6.1. Overview
                              8.4.6.2. Financial Performance
                              8.4.6.3. Product Benchmarking
                              8.4.6.4. Strategic Initiatives
                          8.4.7. Corning Incorporated
                              8.4.7.1. Overview
                              8.4.7.2. Financial Performance
                              8.4.7.3. Product Benchmarking
                              8.4.7.4. Strategic Initiatives
                          8.4.8. Meissner Filtration Products, Inc.
                              8.4.8.1. Overview
                              8.4.8.2. Product Benchmarking
                              8.4.8.3. Strategic Initiatives
                          8.4.9. Lonza
                              8.4.9.1. Overview
                              8.4.9.2. Financial Performance
                              8.4.9.3. Product Benchmarking
                              8.4.9.4. Strategic Initiatives
                          8.4.10. PBS Biotech, Inc.
                              8.4.10.1. Overview
                              8.4.10.2. Product Benchmarking
                              8.4.10.3. Strategic Initiatives

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