Urothelial Cancer Drugs Market Size, Share & Trends Analysis Report By Treatment Class (Chemotherapy, Immunotherapy), By Major Markets}- Global Industry Analysis, Share, Growth, Regional Outlook and Forecasts, 2022-2030

The global Urothelial Cancer Drugs market size was estimated at USD 2.9 billion in 2021 and is expected to surpass around USD 7.9 billion by 2030 and poised to grow at a compound annual growth rate (CAGR) of 24.2% during the forecast period 2022 to 2030.

Growth Factors:

 The U.S. held the dominant share among the seven major markets. Market growth is largely attributed to factors such as availability of novel drugs, the presence of a strong pipeline, rise in the incidence of urothelial cancer due to the growing geriatric population, unorganized lifestyle, and rising public awareness. Urothelial carcinoma or transitional cell carcinoma is a malignant neoplasm occurring from urothelium. The disease is the ninth most common malignancy in the world, with approximately 2.5 million patients and 420,000 newly diagnosed cases each year. Bladder transitional cell carcinoma (TCC) accounted for approximately 90% of all urinary cancer cases.

Urothelial cancer is clinically divided into three categories: non-muscle invasive bladder cancer (NMIBC, early-stage), muscle-invasive disease (MIBC, mid-stage), and metastatic disease (late-stage). At diagnosis, approximately 70% of cases are non-muscle invasive disease, 20% are at the muscle-invasive stage, and 10% at the advanced stage.

Approximately 59% of bladder cancer cases occur in developed regions such as North America and Europe. The economic and human toll of urothelial cancer represents a highly disproportionate health burden.  The disease has the highest lifetime cost of care per patient among all tumors in the U.S. due to its high relapse rate and invasive lifelong monitoring including cystoscopy follow-ups.

Report Scope of the Urothelial Cancer Drugs Market

Report Coverage


Market Size

US$ 7.9 Billion by 2030

Growth Rate

CAGR of 24.2% from 2022 to 2030

Largest Market

North America

Fastest Growing Market

Asia Pacific

Base Year


Forecast Period

2022 to 2030

Segments Covered

 Treatment class and Region,

Companies Mentioned

 Roche; Merck; Bristol-Myers Squibb; AstraZeneca; Pfizer.


Urothelial Cancer Drugs Market Trends

The growing global geriatric population is a major factor propelling the market growth. According to World Health Organization, the population of people over 60 years of age is estimated to be 1.9 billion in 2020. Moreover, in 2050, this number is expected to reach 2.9 billion. This factor is expected to propel industry growth during the forecast period.

Moreover, increasing awareness among the population regarding early treatment and diagnosis for related disorders, coupled with the steady shift towards unhealthy diets and sedentary lifestyles, is driving the market demand. Advancements in drug development have enabled physicians to administer drugs directly to the infected tissues without harming surrounding healthy tissues, which has contributed to increasing patient compliance, which in turn is expected to boost industry growth.

The high research and development cost associated with the manufacturing of urothelial cancer drugs, coupled with increased penetration of generic drugs, is likely to hamper the market growth. However, technological advancements in drug development to manufacturing cost-effective and side-effect-free drugs are anticipated to create opportunities for industry movements.

Treatment Class Insights

Early-stage of urothelial cancer is generally treated with transurethral resection (TURBT), followed by intravesical therapy to reduce recurrence. Partial or radical cystectomy may be recommended in high-grade cancer, multiple tumor sites, or large tumor size at the time of diagnosis. However, relapse rates after surgical resection is high. The standards of care are generic chemotherapeutics, Bacillus Calmette-Guérin (BCG) immunotherapy, and mitomycin C for NMIBC and Gemcitabine-Cisplatin for muscle-invasive disease and metastatic disease.

The treatment landscape for patients with urothelial cancer has undergone multiple changes in the past year, due to the development of PD-1/PD-L1 inhibitors. Combination regimens, particularly checkpoint inhibitors, are likely to become first-line treatment to target key unmet market-needs such as curbing tumor resistance, enhancing progression-free survival, and bettering the quality of life. There remain plenty of opportunities for BCG-intolerant or ineligible patients in the non-muscle invasive bladder cancer (NMIBC) setting.

Pipeline Insights

Disease progression and recurrence rates remain high among patients with aggressive carcinoma in-situ (CIS) classification. The future urothelial cancer treatment landscape has a high probability of gaining an array of first-in-class therapies and it is anticipated that several novel treatments will gain approvals during the forecast period.

The potential for the use of immunotherapies in adjuvant and neoadjuvant settings is now the subject of several clinical trials. These treatments will be used in conjunction with standard therapies to provide patients with safer and effective treatment options. Innovative treatments such as CAR-T therapies and viral therapy continue to generate interest as a potential treatment of urothelial cancer.

Country Insights

The U.S. dominated the urothelial cancer drugs market in 2021, followed by Germany. The U.S. is estimated to retain its leading position in 2030, followed by Japan. Presence of a large target population increased adoption of novel therapeutics, and impending product launches during the forecast period will fuel the market.

China offers a strong opportunity for market expansion. Factors such as high unmet clinical needs and the presence of a large target population are expected to propel the market in this region. Several local players are currently evaluating products as second/third-line treatments in Phase II trials and are well-positioned to be launched in the China market in the upcoming years.

Some of the prominent players in the Urothelial Cancer Drugs Market include:

Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2017 to 2030. For this study, Nova one advisor, Inc. has segmented the global Urothelial Cancer Drugs market

  • Treatment Class
    • Chemotherapy
    • Immunotherapy

By Geography

North America

  • U.S.
  • Canada


  • Germany
  • France
  • United Kingdom
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Southeast Asia
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Rest of Latin America

Middle East & Africa (MEA)

  • GCC
  • North Africa
  • South Africa
  • Rest of Middle East & Africa

Key Points Covered in Urothelial Cancer Drugs Market Study:

  • Growth of Urothelial Cancer Drugs in 2022
  • Market Estimates and Forecasts (2017-2030)
  •  Brand Share and Market Share Analysis
  •  Key Drivers and Restraints Shaping Market Growth
  •  Segment-wise, Country-wise, and Region-wise Analysis
  •  Competition Mapping and Benchmarking
  •  Recommendation on Key Winning Strategies
  •  COVID-19 Impact on Demand for Urothelial Cancer Drugs and How to Navigate
  •  Key Product Innovations and Regulatory Climate
  •  Urothelial Cancer Drugs Consumption Analysis
  •  Urothelial Cancer Drugs Production Analysis
  •  Urothelial Cancer Drugs and Management