U.S. Nerve Repair And Regeneration Market Size, Share & Trends Analysis Report By Surgery (Nerve Grafting, Stem Cell Therapy), By Product (Biomaterials Neurostimulation & Neuromodulation Device), And Segment- Industry Analysis, Share, Growth, Regional Outlook and Forecasts, 2024-2033

The U.S. nerve repair and regeneration market size was estimated at USD 5.85 billion in 2023 and is projected to hit around USD 18.01 billion by 2033, growing at a CAGR of 11.9% during the forecast period from 2024 to 2033.

U.S. Nerve Repair And Regeneration Market Size, 2024 to 2033

Key Takeaways:

  • The neurostimulation and neuromodulation devices segment held the largest market share of 66.09 % in 2023.
  • The biomaterials segment is expected to grow at the highest CAGR during the forecast period.
  • The neurostimulation and neuromodulation surgeries segment held the largest market share of 39.12 % in 2023.
  • The stem cell therapy segment is expected to grow at the highest CAGR during the forecast period. 

U.S. Nerve Repair And Regeneration Market Growth

This is due to the rising prevalence of neurological disorders coupled with the increasing geriatric population in the region. Moreover, stimulation therapy is being increasingly preferred over conventional therapies owing to the presence of Medicare and third-party insurers. Furthermore, the presence of key market players involved in extensive R&D of new products is fueling the market growth.

The U.S. accounted for 28.28% of the nerve repair and regeneration market in 2023. The presence of major competitors & sophisticated healthcare infrastructure and supportive government initiatives are also responsible for market growth in the country. For instance, in 2019, the FDA designated the Checkpoint BEST (Brief Electrical Stimulation Therapy) system as a Breakthrough Device which is intended to deliver electrical stimulation of peripheral nerves to encourage nerve regeneration, and to speed and improve patient recovery.Furthermore, the National Institute of Neurological Disorders and Stroke (NINDS) supports research activities on deep brain stimulation devices as an alternative treatment for PD.

Furthermore, increasing investments for conducting R&D on PD has helped raise awareness and boost the development of new & innovative products and therapies for the treatment of this disease. For instance, the National Parkinson Foundation (NPF) funds researchers and scientists intending to make advancements in this field. Extensive research activities for the inclusion and approval of stimulation devices in new application areas, such as depression and full-body MRI scans, are anticipated to boost market growth over the forecast period.

As per a research article published in Technology Networks, peripheral nerve damage is projected to affect more than 20 million people in the U.S. The same source states that every year, around 700,000 people in the U.S. have surgical treatments to repair severe peripheral nerve injury. Thus, the increasing incidence of nerve injuries is leading to a high demand for nerve repair and regeneration products. Additionally, geriatrics are an important segment of the entire patient pool because of their greater vulnerability. Thus, the increase in the geriatric population boosts the need for nerve repair and regeneration therapy, thereby driving market growth.

U.S. Nerve Repair And Regeneration Market Report Scope

Report Attribute Details
Market Size in 2024 USD 6.55 Billion
Market Size by 2033 USD 18.01 Billion
Growth Rate From 2024 to 2033 CAGR of 11.9%
Base Year 2023
Forecast Period 2024 to 2033
Segments Covered Product, surgery 
Market Analysis (Terms Used) Value (US$ Million/Billion) or (Volume/Units)
Report Coverage Revenue forecast, company ranking, competitive landscape, growth factors, and trends
Key Companies Profiled AxoGen, Inc.; Stryker Corporation; St. Jude Medical, Inc.; Baxter International, Inc.; Polyganics B.V.; Boston Scientific, Inc.; Integra Lifesciences Corporation; Cyberonics, Inc.; Medtronic plc.

 

Segments Insights:

Product Insights

The neurostimulation and neuromodulation devices segment held the largest market share of 66.09 % in 2023 owing to wide applications. These are noninvasive methods used only in cases of unmanageable chronic pain caused by conditions such as Complex Regional Pain Syndrome (CRPS), Intractable Angina Pectoris (IAP), and Peripheral Vascular Disease (PVD). Key industry players are launching new and better technologies which is expected to positively impact the market growth during the forecast period. For instance, in January 2021, Boston Scientific Corporation received U.S. FDA approval for its fourth-generation Vercise Genus Deep Brain Stimulation (DBS) System for conditional use in a magnetic resonance imaging (MRI) environment.

The biomaterials segment is expected to grow at the highest CAGR during the forecast period. This growth is attributed to technological advancements, a wide range of applications, government funding for innovations, and a rise in implantable device applications. Advanced products such as biodegradable polymers are expected to enhance spinal stabilization, healing of fractures, and reduce hospitalization which is projected to further enhance the market growth.

Surgery Insights

The neurostimulation and neuromodulation surgeries segment held the largest market share of 39.12 % in 2023. The rising number of lower back pain patients is accompanying the high rates of disabilities. The regular approvals and wider applications of these surgeries are promoting regenerative surgeries. FDA approvals for deep brain stimulation devices are fueling the market growth. For instance, in March 2020, NeuroPace, Inc. received approval from the U.S. FDA for MRI labeling for its Responsive Neurostimulation Device (RNS) system.

The stem cell therapy segment is expected to grow at the highest CAGR during the forecast period as it is perceived as the backbone of regenerative medicine. The segment also witnesses several R&D activities along with an increase in government initiatives and approvals to conduct clinical trials. These factors are also anticipated to fuel the market growth.

Recent Developments

  • In January 2022, the U.S. FDA approved the rechargeable Intellis neurostimulator and the recharge-free Vanta neurostimulator by Medtronic plc for the treatment of Diabetic Peripheral Neuropathy (DPN)-related chronic discomfort
  • In March 2022, Integra LifeSciences launched NeuraGen 3D Nerve Guide Matrix, a resorbable implant for the repair of peripheral nerve discontinuities. It is a nerve repair product specifically engineered to create an optimized environment that may allow for a more complete functional recovery following mid-gap nerve repair when compared to hollow nerve conduits alone
  • In September 2023, Axogen, Inc. announced the complete launch of Axoguard HA+ Nerve Protector which is an important extension of our nerve protection platform designed to provide both short- and long-term protection for peripheral nerve injuries

Key U.S. Nerve Repair And Regeneration Company Insights

Some of the prominent U.S. nerve repair and regeneration companies include NeuroPace, Inc., Medtronic, Stryker, AxoGen Corporation, Abbott (ST. Jude Medical), Baxter International (Synovis Micro Companies Alliance, Inc.), Boston Scientific Corporation, Polyganics, and Integra LifeSciences. New product launches and mergers & acquisitions are the key strategic undertakings of the participants in this vertical.

Innovation and new product development are expected to play a crucial role for the market players. Market players are in the process of introducing advanced products to capture a higher market share. There is a high demand for advanced specialized products with high technical capabilities which require more capital, and this is expected to restrict the entry of new players.

Key U.S. Nerve Repair And Regeneration Companies:

  • AxoGen, Inc.
  • Stryker Corporation
  • St. Jude Medical, Inc.
  • Baxter International, Inc.
  • Polyganics B.V.
  • Boston Scientific, Inc.
  • Integra Lifesciences Corporation
  • Cyberonics, Inc.
  • Medtronic plc.
  • Comp10

Segments Covered in the Report

This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Nova one advisor, Inc. has segmented the U.S. Nerve Repair And Regeneration market.

By Product 

  • Biomaterials
  • Neurostimulation And Neuromodulation Devices
    • Spinal Cord Stimulation Devices
    • Deep Brain Stimulation Devices
    • Sacral Nerve Stimulation Devices
    • Vagus Nerve Stimulation Devices
    • Gastric Electric Stimulation Devices

By Surgery

  • Direct Nerve Repair/Neurorrhaphy
  • Nerve Grafting
  • Stem Cell Therapy
  • Neurostimulation And Neuromodulation Surgeries

Frequently Asked Questions

The U.S. nerve repair and regeneration market size was estimated at USD 5.85 billion in 2023 and is projected to hit around USD 18.01 billion by 2033

The U.S. nerve repair and regeneration market is expected to grow at a compound annual growth rate of 11.6% from 2024 to 2033

.Some of the key players in the U.S. nerve repair and regeneration market include are AxoGen, Inc.; Stryker Corporation; St. Jude Medical, Inc.; Baxter International, Inc.; Polyganics B.V.; Boston Scientific, Inc.; Integra Lifesciences Corporation; Cyberonics, Inc.; Medtronic plc.

Rising cases of neurological disorders and a strong product pipeline by the major companies are the key factors driving the market. Improved treatment efficiency for neurological disorders due to several technological advancements is also likely to contribute to the market growth.

Chapter 1 U.S. Nerve Repair And Regeneration Market: Methodology and Scope
                   1.1 Market Segmentation & Scope
                   1.2 Research Methodology
                   1.3 Information Procurement
                       1.3.1 Purchased Database
                       1.3.2 nova one advisor Internal Database
                       1.3.3 Secondary Sources
                       1.3.4 Primary Research
                   1.4 Information or Data Analysis
                   1.5 Market Formulation & Validation
                   1.6 Model Details
                       1.6.1 Commodity Flow Analysis (Model 1)
                       1.6.2 Volume Price Analysis (model 2)
                   1.7 List of Secondary Sources
                   1.8 List of Abbreviations
                   1.9 Objectives
                       1.9.1 Objective - 1
                       1.9.2 Objective - 2
Chapter 2 U.S. Nerve Repair And Regeneration Market: Executive Summary
                   2.1 Market Outlook
                   2.2 Segment Outlook
                   2.3 Competitive Landscape Outlook
Chapter 3 U.S. Nerve Repair And Regeneration Market: Variables, Trends & Scope
                   3.1 Market Lineage outlook
                       3.1.1 Parent Market Outlook
                   3.2 Market Segmentation
                   3.3 Penetration & Growth Prospect Mapping
                       3.3.1 Penetration & Growth Prospect Mapping
                   3.4 Regulatory Framework & Reimbursement Scenario
                   3.5 Market Dynamics
                       3.5.1 Market Driver Analysis
                           3.5.1.1 Increasing government fundings and reimbursements
                           3.5.1.2 Increasing incidences of the neurological disorders
                           3.5.1.3 Rising medical tourism
                       3.5.2 Market Restraint Analysis
                           3.5.2.1 Lack of awareness in the patients for treatment of nerve repair and regeneration
                           3.5.2.2 High cost of the treatment and unavailability of trained medical personnel
                   3.6 Business Environment Analysis Tools
                       3.6.1 Porter’s Five Forces Analysis
                           3.6.1.1 Bargaining power of buyers: Moderate
                           3.6.1.2 Bargaining power of suppliers: Low
                           3.6.1.3 Competitive rivalry: High
                           3.6.1.4 Threat of new entrants: Moderate
                           3.6.1.5 Threat of substitutes: Moderate
                       3.6.2 PESTEL Analysis
                           3.6.2.1 Political & legal landscape
                           3.6.2.2 Economic landscape
                           3.6.2.3 Social landscape
                           3.6.2.4 Technological landscape
                           3.6.2.5 Environmental landscape
                   3.7 Major Deals & Strategic Alliances Analysis
                       3.7.1 Mergers & Acquisitions
                       3.7.2 Licensing & Partnership
Chapter 4 U.S. Nerve Repair And Regeneration Market: Product Analysis
                   4.1 Nerve Repair And Regeneration Product Market Share Analysis, 2022
                   4.2 Nerve Repair And Regeneration Product Market: Segment Dashboard:
                   4.3 Market Size & Forecasts And Trend Analyses, 2018 To 2030 For The Product Segment
                       4.3.1 Biosimilars
                           4.3.1.1 Biosimilars market, 2021 - 2033
                       4.3.2 Neurostimulation & Neuromodulation Devices
                           4.3.2.1 Spinal cord stimulation devices market, 2021 - 2033
                           4.3.2.2. Deep brain stimulation devices market, 2021 - 2033
                           4.3.2.3 Sacral nerve stimulation devices market, 2021 - 2033
                           4.3.2.4 Vagus nerve stimulation devices market, 2021 - 2033
                           4.3.2.5 Gastric electric stimulation devices market, 2021 - 2033
Chapter 5 U.S. Nerve Repair And Regeneration Market: Surgery Analysis
                   5.1 Nerve Repair And Regeneration Surgery Market Share Analysis, 2022
                   5.2 Nerve Repair And Regeneration Surgery Market: Segment Dashboard
                   5.3 Market Size & Forecasts And Trend Analyses, 2018 - 2030 For The Surgery
                       5.3.1 Direct Nerve Repair/Neurorrhaphy
                           5.3.1.1 Direct nerve repair/Neurorrhaphy market, 2021 - 2033
                       5.3.2 Nerve Grafting
                           5.3.2.1 Nerve grafting market, 2021 - 2033
                       5.3.3 Stem Cell Therapy
                           5.3.3.1 Stem cell therapy market, 2021 - 2033
                       5.3.4 Neurostimulation & Neuromodulation Surgeries
                           5.3.4.1 Neurostimulation & neuromodulation surgeries market, 2021 - 2033
Chapter 7 Competitive Analysis
                   7.1 Recent Developments & Impact Analysis, By Key Market Participants
                   7.2 Strategic Framework/ Competition Categorization (Key Innovators, Market Leaders, Emerging Players
                   7.3 Vendor Landscape
                   7.4 Public Companies
                       7.4.1 Company Market Position Analysis (Revenue, Geographic Presence, Product Portfolio, Strategic Initiatives, Employee Strength)
                   7.5 Private Companies
                       7.5.1 Company Market Position Analysis (Geographic Presence, Product Portfolio, Key Alliance, Industry Experience)
                   7.6 Company Profiles
                       7.6.1 CYBERONICS, INC
                           7.6.1.1 Company overview
                           7.6.1.2 Financial performance
                           7.6.1.3 Product benchmarking
                           7.6.1.4 Strategic initiatives
                           7.6.1.5 SWOT Analysis
                       7.6.2 MEDTRONIC
                           7.6.2.1 Company overview
                           7.6.2.2 Financial performance
                           7.6.2.3 Product benchmarking
                           7.6.2.4 Strategic initiatives
                           7.6.2.5 SWOT Analysis
                       7.6.3 STRYKER
                           7.6.3.1 Company overview
                           7.6.3.2 Financial performance
                           7.6.3.3 Product benchmarking
                           7.6.3.4 Strategic initiatives
                           7.6.3.5 SWOT Analysis
                       7.6.4 AXOGEN CORPORATION
                           7.6.4.1 Company overview
                           7.6.4.2 Financial performance
                           7.6.4.3 Product benchmarking
                           7.6.4.4 Strategic initiatives
                           7.6.4.5 SWOT Analysis
                       7.6.5 ST. JUDE MEDICAL
                           7.6.5.1 Company overview
                           7.6.5.2 Financial performance
                           7.6.5.3 Product benchmarking
                           7.6.5.4 Strategic initiatives
                           7.6.5.5 SWOT Analysis
                       7.6.6 BAXTER
                           7.6.6.1 Company overview
                           7.6.6.2 Financial performance
                           7.6.6.3 Product benchmarking
                           7.6.6.4 Strategic initiatives
                           7.6.6.5 SWOT Analysis
                       7.6.7 BOSTON SCIENTIFIC CORPORATION
                           7.6.7.1 Company overview
                           7.6.7.2 Financial performance
                           7.6.7.3 Product benchmarking
                           7.6.7.4 Strategic initiatives
                           7.6.7.5 SWOT Analysis
                       7.6.8 POLYGANICS
                           7.6.8.1 Company overview
                           7.6.8.2 Financial performance
                           7.6.8.3 Product benchmarking
                           7.6.8.4 Strategic initiatives
                       7.6.9 INTEGRA LIFESCIENCES
                           7.6.9.1 Company overview
                           7.6.9.2 Financial performance
                           7.6.9.3 Product benchmarking
                           7.6.9.4 Strategic initiatives
                           7.6.9.5 SWOT Analysis

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